DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3061 and dnajc18

DIOPT Version :9

Sequence 1:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001107060.1	Gene:	dnajc18 / 559928	ZFINID:	ZDB-GENE-030131-8019	Length:	407	Species:	Danio rerio

Alignment Length:	399	Identity:	142/399 - (35%)
Similarity:	230/399 - (57%)	Gaps:	38/399 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLL-AQLKS--TPSNESNGKSRTA 65
            :::|:.|.|:.|...|.:|:.|||.:.|.:|::::|:..|:.|: |.:|:  ||.::....:...
Zfish     7 DREESDRLIEKAKLCLRSGRKEKALQLLYEAQKIYPSTRARVLIDAIVKNGYTPPDDERTYTPPP 71

  Fly    66 G--ASDE--KDSGPRKRVNSDSR--SSAPD---YTKDQLEAVRKVKTCKDYYEVLGVSKTATDSE 121
            |  ::||  ..|.|..|.::..|  :||.|   ||::|.:.|.::|.|:|:||:|||.|.|:|.:
Zfish    72 GWRSADEDVPPSVPHHRPSTHERAEASADDKKSYTEEQRQGVLRIKKCRDFYEILGVPKGASDED 136

  Fly   122 IKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNGHGNNGGGHH 186
            :||||:||||:.|||||.||||.:||||:|||..||::.|||:.||.||    ..|.........
Zfish   137 LKKAYRKLALRFHPDKNCAPGATDAFKAIGNAYAVLSNPEKRQQYDEYG----DQGPAETSSQPS 197

  Fly   187 GH-GQYYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVHMRQ------------------QRR 232
            .. .|.|.....::|.|:.|||.|||||:||.|.||..|:|:..                  :||
Zfish   198 AQPRQAYARHRSFTRDFEPDISPEELFNIFFGGRFPTGNIHVYTNGGASYAHYYQPRRRRPFERR 262

  Fly   233 RQQAREDREGNNSSALVNLLPIVLLIGLSMMSSFFISDPMYSL--TPSHKYSVKRETNSLKVPYY 295
            .::..|....||.:.|:.|||:::||.:|:.:....::|.|||  .||....|.|||..:.||||
Zfish   263 EEEVEESHSTNNFTPLLQLLPVLVLIVISVFTQLMATNPPYSLFYKPSMGLVVSRETQHMGVPYY 327

  Fly   296 VKDNFYSEYQG-SVARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTP 359
            |..:|..||:| ::..||:::|.|:::||:.||.:|:..:..:....:.:.|..|.:||:.:...
Zfish   328 VDKSFEKEYRGAALDELEKTIETDYIDHLQSSCWKEKQQKSDLANLGQLYRDERLKQKAETMKLD 392

  Fly   360 SCENLQKYL 368
            .|:.|.:::
Zfish   393 HCDKLHRFI 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	60/119 (50%)
		DnaJ	106..167	CDD:278647	38/60 (63%)
		DUF1977	269..366	CDD:286411	34/99 (34%)
dnajc18	NP_001107060.1	DnaJ	121..182	CDD:278647	38/60 (63%)
dnajc18	NP_001107060.1	DUF1977	299..399	CDD:286411	34/99 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589193
Domainoid	1	1.000	93	1.000	Domainoid score	I7495
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55696
OrthoDB	1	1.010	-	-		D1173544at2759
OrthoFinder	1	1.000	-	-		FOG0001005
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43908
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2148
SonicParanoid	1	1.000	-	-		X535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.850