DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3061 and dnajb12

DIOPT Version :9

Sequence 1:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001015991.1	Gene:	dnajb12 / 548745	XenbaseID:	XB-GENE-944288	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	391	Identity:	177/391 - (45%)
Similarity:	247/391 - (63%)	Gaps:	54/391 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQL--KSTPSNESNGKSR 63
            |:.|:|||:|||..|:.|:.:...|||.:||.||:|||||:.|:.|...|  ||.|.|..:..:.
Frog     1 MESNRDEAERCIAIALGAIKSQNTEKALRFLEKAQRLFPTERAQALYESLSQKSQPENSQSDSTE 65

  Fly    64 TAGASDEKDSGPRKRVN-SDSRSSA---------PDYTKDQLEAVRKVKTCKDYYEVLGVSKTAT 118
            |        :.||.|.| :||..||         ..||.||||||:::|.||||||:|||::.||
Frog    66 T--------TNPRLRKNAADSTPSANGEAGGETGKSYTPDQLEAVKRIKQCKDYYEILGVTREAT 122

  Fly   119 DSEIKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYG---INESHNGHGN 180
            :.::||:|:||||:.|||||.||||.|||||:|||..||::.||||.||.:|   ::.|.:||.:
Frog   123 EDDLKKSYRKLALKFHPDKNHAPGATEAFKAIGNAYAVLSNTEKRKQYDQFGEEKVSSSRHGHSD 187

  Fly   181 NGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVH------MRQQRRRQQARED 239
                             :.|||:||||.|:||||||.||||..|||      ||....::|.|.:
Frog   188 -----------------FHRGFEADISPEDLFNMFFGGGFPASNVHVYSNGRMRYTYPQRQDRRE 235

  Fly   240 REGNNSSAL-VNLLPIVLLIGLSMMSSFFISDPMYSLTPSHKYSV----KRETNSLKVPYYVKDN 299
            .:|:.:..: |.|:||::||.:|.:|...:|.|.|||  ||:.||    :|.|..|||||:|.|:
Frog   236 HQGDGTLGMFVQLMPILILIIVSALSQMMVSTPPYSL--SHRPSVGHIHRRVTEHLKVPYFVTDS 298

  Fly   300 FYSEYQGSVAR-LEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCEN 363
            |..||.||..| :|.|||:||:.:|:::|.:|:..::.:|.:||.|||.|||::||.:.||||..
Frog   299 FDEEYTGSNLRSVERSVEDDFIANLRNNCWKEKQQKEGLLYRARYFGDSDLYQRAQRMGTPSCSR 363

  Fly   364 L 364
            |
Frog   364 L 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	64/121 (53%)
		DnaJ	106..167	CDD:278647	39/60 (65%)
		DUF1977	269..366	CDD:286411	49/101 (49%)
dnajb12	NP_001015991.1	DnaJ	110..171	CDD:278647	39/60 (65%)
dnajb12	NP_001015991.1	DUF1977	266..364	CDD:286411	48/99 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7347
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9749
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2546
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1173544at2759
OrthoFinder	1	1.000	-	-		FOG0001005
OrthoInspector	1	1.000	-	-		otm48260
Panther	1	1.100	-	-	LDO	PTHR43908
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2148
SonicParanoid	1	1.000	-	-		X535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190