DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3061 and SPBC17A3.05c

DIOPT Version :9

Sequence 1:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_595587.1	Gene:	SPBC17A3.05c / 2540130	PomBaseID:	SPBC17A3.05c	Length:	403	Species:	Schizosaccharomyces pombe

Alignment Length:	412	Identity:	139/412 - (33%)
Similarity:	209/412 - (50%)	Gaps:	67/412 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQL-----------KSTP 54
            |:.:::||.|||..|.:.|.||:.:||.||..|:.|:..|...:..:.|:           ::||
pombe     1 MESSREEALRCIGLARKYLNAGEYDKALKFANKSLRIHATTEGEDFVKQIEKQKLTGSPNPQATP 65

  Fly    55 --SNESNGKSRTAGASDEKDSGPRKRVNSDSRSSAPDYTKDQLEAVRKVKTCKD--YYEVLGVSK 115
              .|:||..|       ||.| .|:..||.:......:|.:|...|:|:...|:  |||:|.:.|
pombe    66 KQENKSNFFS-------EKQS-VRENGNSSAGEKKQKWTSEQHLLVQKIIKYKNHQYYEILDLKK 122

  Fly   116 TATDSEIKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGIN-ESH---- 175
            |.||:||||:|||||||||||||.||.|.||||.:..|..||:|...|.:||..|:: ||.
pombe   123 TCTDTEIKKSYKKLALQLHPDKNHAPSADEAFKMVSKAFQVLSDPNLRAHYDRTGMDPESRASAA 187

  Fly   176 -NGHGNNGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFN------------GGFPQQNVHM 227
             :...:|.|||.|...|.          ||::|.|:|||.||.            ||.|...||.
pombe   188 SSSFSSNAGGHPGFSAYP----------QANMSPEDLFNSFFGDQFFSGPGTFFFGGGPGIRVHQ 242

  Fly   228 -----RQQRRRQQAREDREGNNSSALVNLLPIVLLIGLSMMSSFFISD-----PMYSLTPSHKYS 282
                 |...|||||::...   .|....|||::::|..:.:|:|..||     ..||...::||:
pombe   243 FGGRPRNFARRQQAQDMPP---KSIFYQLLPLIVVILFAFLSNFSWSDSTSVNTRYSFQQNYKYT 304

  Fly   283 VKRETNSLKVPYYVKDNFYSEYQG-SVARLEESVEEDFVNHLKHSCSRERNYRDSMLAKAR--TF 344
            |.|.|....:|||:......:... .:.||.|.||..:..::.::|.||:..::..:.:|:  .|
pombe   305 VPRTTAKHNIPYYMSQKDLDKLSSRDIRRLNEKVEHTYTQNVHNACLREQQIKEDEIRRAQGWFF 369

  Fly   345 GDRDLYRKAQNINTPSCENLQK 366
            .|::..:||:.:..|:||.|.:
pombe   370 PDKEALKKAKELRLPNCEELNR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	61/138 (44%)
		DnaJ	106..167	CDD:278647	37/62 (60%)
		DUF1977	269..366	CDD:286411	29/104 (28%)
SPBC17A3.05c	NP_595587.1	DnaJ	114..>220	CDD:223560	56/115 (49%)
		DnaJ	114..174	CDD:278647	37/59 (63%)
		DUF1977	295..391	CDD:286411	27/95 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	81	1.000	Domainoid score	I2330
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1054
OMA	1	1.010	-	-		QHG55696
OrthoFinder	1	1.000	-	-		FOG0001005
OrthoInspector	1	1.000	-	-		oto101038
orthoMCL	1	0.900	-	-		OOG6_101281
Panther	1	1.100	-	-	LDO	PTHR43908
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2148
SonicParanoid	1	1.000	-	-		X535
TreeFam	1	0.960	-	-
	13	12.860