Protein Alignment Cyp6d5 and ERG11

DIOPT Version :9

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 504
• Identity: 120/504 - (23%)
• Similarity: 195/504 - (38%)
• Gaps: 119/504 - (23%)

  Fly     7 LIAAVTLLYVYLKWTFSYWDRKGFPS-TGVSIPFGALESVTKGKRSFGMAIYDMYKSTKEP---- 66
            ||..:..:| .:.|...|..||..|. ....||:.....|      :||..|:.::..::.
Yeast    33 LIIIIPFIY-NIVWQLLYSLRKDRPPLVFYWIPWVGSAVV------YGMKPYEFFEECQKKYGDI 90

  Fly    67 --------VIGLYLTLRPALLVRDAQLAHDVLVKDFASFH------DRGVYVDEKNDPMSASLFQ 117
                    |:.:||..:....|.:|:|| ||.. :.|..|      .:||..|..|.
Yeast    91 FSFVLLGRVMTVYLGPKGHEFVFNAKLA-DVSA-EAAYAHLTTPVFGKGVIYDCPNS-------- 145

  Fly   118 MEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDI 182
                  |.:..|   .|..|.|..  |...|....:.:.:.|..  ..:|...|.: ..|..||:
Yeast   146 ------RLMEQK---KFVKGALTK--EAFKSYVPLIAEEVYKYF--RDSKNFRLNE-RTTGTIDV 196

  Fly   183 IAT----TIFGLDVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGW----- 238
            :.|    |||          .....::.|::......|.     ::||..|:|.|..|.:
Yeast   197 MVTQPEMTIF----------TASRSLLGKEMRAKLDTDF-----AYLYSDLDKGFTPINFVFPNL 246

  Fly   239 ----KQEATERMRELSNRTVDL----REQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNG 295
                .::.....:.:|...:.|    |:.|:|..:||:               |::....:.|:|
Yeast   247 PLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLI---------------DSLMKNSTYKDG 296

  Fly   296 VKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGK--LTYD 358
            || |:...||..|....:.|..|:|:|:::.|..|.:.|:|.::..|:....::  |||  ||||
Yeast   297 VK-MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLD--GGKKELTYD 358

  Fly   359 AISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDP 423
            .:.:|..|...|.||.|.:..|..|.|...||..||::..||..|..:::|....|..:||||:.
Yeast   359 LLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNA 423

  Fly   424 LAYKPERYLENGK---------DY--------TQAAYLPFGEGPRMCIG 455
            ..:...|:.::..         ||        ..:.|||||.|...|||
Yeast   424 HQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	106/444 (24%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	106/447 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960