DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6d5 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_650327.1	Gene:	Cyp6d5 / 41706	FlyBaseID:	FBgn0038194	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	127/546 - (23%)
Similarity:	236/546 - (43%)	Gaps:	111/546 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IGIYLLIAAVTLLYVYLKWTFSYWDRKGF--PSTGVSIP-FGALESVTKGK---RSFGMAIYDMY 60
            |.|::|:.    |:.:|.:...:...|||  |.:..|:| .|.|..:....   :||....:..
plant    12 ISIFILLC----LFSFLCYALFFKKPKGFDLPPSPPSLPIIGHLHHLLSSSLPHKSFQKLSFKY- 71

  Fly    61 KSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQME--GASW 123
                .|::.|.:...|.:||..|.:|::|...:..:...|.|.|::.:....:|.|...  |..|
plant    72 ----GPLLHLRIFNFPMVLVSSASMAYEVFRTNDVNVSYRFVPVNKDSLVFGSSGFVTAPYGDYW 132

  Fly   124 RALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIF 188
            :.::          ||         :..||:.....:| :.|.:..||::              |
plant   133 KFMK----------KL---------ISTKLLRPHALEL-SKGNRAEELRR--------------F 163

  Fly   189 GLDVDSFADPNNEFQI--ISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERMRELSN 251
            .||:...|......:|  ::.|:..|.|..:..|.|             ...|....||.|||.|
plant   164 CLDLQGKARKKESVEIGKVALKLTNNIICRMSMGRS-------------CSEKNGVAERARELVN 215

  Fly   252 RTVDLREQ---NNIVRKDLL-----------QLLLQLRN--QGKINTD--DNIWSAESTKNGVKS 298
            ::..|..:   :|:.|||::           ::|::...  :|..:.|  |::..|...:.....
plant   216 KSFALSVKLFFSNMFRKDIMGVSREFDEFLERILVEHEENLEGDQDRDMIDHLLEAYRNEEAEYK 280

  Fly   299 MSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGK--LTYDAIS 361
            :::..|...:...::.|.:::|.|..:|:.|:..||.|:||.:.::.|.:   |||  :....:.
plant   281 ITRKQIKSLIVEIFLGGTDSSAQTIQWTMAEILNNPGVLEKLRAEIDSVV---GGKRLIQESDLP 342

  Fly   362 DMKYLEACILETARKYPALPLLNRI----C-TKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFP 421
            ::.||:|.:.|..|.:|:.|:|.|:    | .|::.||:.       |.::::|..::||.:.:.
plant   343 NLPYLQAVVKEGLRLHPSAPVLLRVFGESCEVKEFYVPEK-------TTLVVNLYAVNRDPDSWE 400

  Fly   422 DPLAYKPERYL------ENGKDYTQAA-YLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIR 479
            ||..:||||:|      :..|...||. |:.||.|.|.|...::..:.::.||..::..||..|:
plant   401 DPDMFKPERFLVSSISGDEEKIREQAVKYVTFGGGRRTCPAVKLAHIFMETAIGAMVQCFDWRIK 465

  Fly   480 KEKCEIEFGVYGIPLM---PKSGVPV 502
            .||..:|..|.|:.|.   |....||
plant   466 GEKVYMEEAVSGLSLKMAHPLKCTPV 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	102/447 (23%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	110/474 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010