DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6d5 and CYP735A1

DIOPT Version :9

Sequence 1:	NP_650327.1	Gene:	Cyp6d5 / 41706	FlyBaseID:	FBgn0038194	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_198661.1	Gene:	CYP735A1 / 833833	AraportID:	AT5G38450	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	137/550 - (24%)
Similarity:	227/550 - (41%)	Gaps:	97/550 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLIAAVTLLYVYLKWTFSYW----------DRKGF------PSTGVSIPFGALESVTKGKRSFGM 54
            |:|...|:|.|.......||          :::|.      |.||..:...|:.|.:..|..
plant    10 LVIFVTTILRVLYDTISCYWLTPRRIKKIMEQQGVTGPKPRPLTGNILEISAMVSQSASKDC--- 71

  Fly    55 AIYDMYKSTKEPVIGLYLT------------------LRPALLVRDAQLAHDVLVKDFASFHDRG 101
                  .|....::|..|.                  ..|.|.:.:.:|..::|:|     |: |
plant    72 ------DSIHHDIVGRLLPHYVAWSKQYGKRFIVWNGTDPRLCLTETELIKELLMK-----HN-G 124

  Fly   102 V----YVDEKNDP--MSASLFQMEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQ 160
            |    ::.::...  :...|....|..|...|:...|:||..:||...........|||:.:||:
plant   125 VSGRSWLQQQGTKNFIGRGLLMANGQDWHHQRHLAAPAFTGERLKGYARHMVECTSKLVERLRKE 189

  Fly   161 LPANGAKELELKKLMATYAIDIIATTIFGLDVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFL 225
            : ..||.|:|:.:.|.....|||:.|.||...:...:..|...::.::        ..:.|....
plant   190 V-GEGANEVEIGEEMHKLTADIISRTKFGSSFEKGKELFNHLTVLQRR--------CAQATRHLC 245

  Fly   226 YPGLEKFFVKIGWKQEATERMRELSNRTVDL----REQNNIVRK-----DLLQLLLQLRNQGKIN 281
            :||..  |:...:.:|.....:|:....:::    |:...:.|.     |||.|||...:..|.|
plant   246 FPGSR--FLPSKYNREIKSLKKEVERLLIEIIQSRRDCAEMGRSSTHGDDLLGLLLNEMDIDKNN 308

  Fly   282 TDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRS 346
            .::|        |.::     ||..:...|:.||:||||...::|...|..||...||.:|:||.
plant   309 NNNN--------NNLQ-----LIMDECKTFFFAGHETTALLLTWTTMLLADNPTWQEKVREEVRE 360

  Fly   347 AIEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLI 411
            ...:: |..:.|.:|.:..|...|.|:.|.||...||.|:..:|..:.|  |.|.||..|.|.::
plant   361 VFGRN-GLPSVDQLSKLTSLSKVINESLRLYPPATLLPRMAFEDLKLGD--LTIPKGLSIWIPVL 422

  Fly   412 GMHRDEEYF-PDPLAYKPERYLENGKDYTQAA-YLPFGEGPRMCIGARMGKVNVKIAIAKVLSNF 474
            .:|..||.: .|...:.|||:  .|:.:.... ::||..|||.|||.:...:..||.:|.::|.|
plant   423 AIHHSEELWGKDANQFNPERF--GGRPFASGRHFIPFAAGPRNCIGQQFALMEAKIILATLISKF 485

  Fly   475 DLEIRKEKCEIEFGVYGIPLMPKSGVPVRL 504
            :..|.|........|  :.:.||.||.|.|
plant   486 NFTISKNYRHAPIVV--LTIKPKYGVQVIL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	113/446 (25%)
CYP735A1	NP_198661.1	PLN02290	1..518	CDD:215164	136/549 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910