DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6d5 and CYP705A4

DIOPT Version :9

Sequence 1:	NP_650327.1	Gene:	Cyp6d5 / 41706	FlyBaseID:	FBgn0038194	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_193273.1	Gene:	CYP705A4 / 827204	AraportID:	AT4G15380	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	126/550 - (22%)
Similarity:	220/550 - (40%)	Gaps:	124/550 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLYVYLKWTFSYWDRK--------GFPSTGVSIP-FGAL---------ESVTKGKRSFGMAIYDM 59
            ||.::.:..:|::.:|        ..|.:..|:| .|.|         .|:.|....:|..:|
plant    17 LLCLFSRLCYSHFFKKPKDPRLHFDLPPSPPSLPIIGHLHLLLSVLLHRSLQKLSTKYGSILY-- 79

  Fly    60 YKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQM----EG 120
                      |.:...|.:|:..|.:|:::......:...||  ....:|.:.|..|..    .|
plant    80 ----------LRVFRFPVVLISSASIAYEIFRAHDLNISYRG--FTPTDDSLFAGSFSFISAPYG 132

  Fly   121 ASWRALRNKLTPSFTSGKLKAMFETSDSV---------GDKLVDSIRKQLPANGAKELELKKLMA 176
            ..|:.::..|..:....:   ..|.|..|         |:....:|:||.....|:.|:|..
plant   133 DYWKFMKKVLVTNVFGPQ---AHEQSRGVRADVLERFYGNLFDKAIKKQSVEICAEALKLSN--- 191

  Fly   177 TYAIDIIATTIFG--LDVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWK 239
                ..|...|.|  ...:.|.....|..:::||:...|:          |....:|..|.: :|
plant   192 ----SSICKMIMGRSCSEERFRALATELDVLTKKLFFANM----------LRAWFKKLVVSL-FK 241

  Fly   240 QEAT---ERMREL-------SNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKN 294
            :|.|   .|..||       ..:.:|:..|    |.||:..||....      |:|. ..:.|:|
plant   242 KETTVISYRFDELLESILVEHEKKLDVHHQ----RTDLMDALLAAYR------DENA-EYKITRN 295

  Fly   295 GVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDA 359
            .:||:..||:        .||.|....|..:.:.|:..||.|:|:.:.::.|.:.|  .:|..:.
plant   296 HIKSIIADLL--------FAGTENQVQTIQWAMAEIINNPNVLERLRGEIDSVVGK--SRLIQET 350

  Fly   360 -ISDMKYLEACILETARKYPALPLLNRICTKD------YPVPDSKLVIQKGTPIIISLIGMHRDE 417
             :..:.||:|.:.||.|.:|..|...|. ||:      :.||::       |.:::::..:.||.
plant   351 DLPKLPYLQAVVKETIRLHPPGPFFLRF-TKEGCRIRGFYVPEN-------TSVVVNVYAVMRDP 407

  Fly   418 EYFPDPLAYKPERYL-------ENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFD 475
            :.:.|||.:||||:|       |..:...:..|||||.|.|.|.|..:..|.:..||..::..|:
plant   408 DAWEDPLVFKPERFLASSRAEQEEERREKEIKYLPFGSGRRSCPGENLAYVIMGTAIGVMVQGFE 472

  Fly   476 LEIRKEKCEIEFGVYGIPLM---PKSGVPV 502
            ....:||..::..|.|:.|.   |...:||
plant   473 WRTTEEKINMDEAVVGLSLTMAHPLKIIPV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	105/450 (23%)
CYP705A4	NP_193273.1	p450	70..508	CDD:386267	114/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010