Protein Alignment Cyp6d5 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 119/497 - (23%)
• Similarity: 227/497 - (45%)
• Gaps: 54/497 - (10%)

  Fly     4 IYLLIAAVTLLYVYLKWTFSYWDR----KGFPSTGVSIPF----GALESVTKGKRSFGMAI--YD 58
            :.||:....||...|.||::::|.    :.||.......|    |.:....:|.::....:  |.
Human    21 LLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYP 85

  Fly    59 M-YKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQMEGAS 122
            . :|....|...|.:...|.::......:..|..||.       ::.......:...|....|..
Human    86 QGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDM-------IFYGFLKPWLGDGLLLSGGDK 143

  Fly   123 WRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIR---KQLPANGAKELELKKLMATYAIDIIA 184
            |...|..|||:|....||...:    :.:|.|:.:.   ::|.:.|:..|::.:.::...:|.:.
Human   144 WSRHRRMLTPAFHFNILKPYMK----IFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQ 204

  Fly   185 TTIFGLDVDSFADPNNEFQII---SKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERM 246
            ..:|..:.:....|:.....|   |..|.:.|.:.::.  :.|||     :....|      :|.
Human   205 KCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLH--TDFLY-----YLTPDG------QRF 256

  Fly   247 RELSNRTVDLREQNNIVRKDLLQLLLQ-----LRNQGKINTDD--NIWSAESTKNGVKSMSKDLI 304
            |...:...|..:.  ::::....|..|     |:|:.|..|.|  ::......::| |.:|.:.|
Human   257 RRACHLVHDFTDA--VIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDG-KELSDEDI 318

  Fly   305 AGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAI-EKHGGKLTYDAISDMKYLEA 368
            ..:...|...|::||||..|:.||.|.::||..|:.:::|:..: ::...::.:|.::.:.:|..
Human   319 RAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTM 383

  Fly   369 CILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-L 432
            ||.|:.|.:|.:|:::|.||:|:.:||.: ||.||...:|::||:|.:...:|||..|.|.|: .
Human   384 CIKESLRLHPPVPVISRCCTQDFVLPDGR-VIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQ 447

  Fly   433 ENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNF 474
            ||.|:.:..|::||..|||.|||.......:|:.:|..|.:|
Human   448 ENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	104/427 (24%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	106/444 (24%)