Protein Alignment Cyp6d5 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 588
• Identity: 112/588 - (19%)
• Similarity: 209/588 - (35%)
• Gaps: 167/588 - (28%)

  Fly     6 LLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPFGALESVTKGKRSF-----GMAIYDMYKSTKE 65
            ||:|...||:.: :|:.:. ||    :..:.:|.|::.....|: :|     |.:.:...:....
Zfish    24 LLLAVSRLLWEF-RWSITR-DR----TCKLPLPQGSMGWPLVGE-TFHWLFQGSSFHISRREKHG 81

  Fly    66 PVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSA-------SLFQMEGASW 123
            .|...:|..:|.:.|..|:....:|:.:..        |.....|.|.       :|....|...
Zfish    82 KVFKTHLLGKPLIRVTGAENIRKILLGEHT--------VVCTQWPQSTRIILGPNTLVNSVGDLH 138

  Fly   124 RALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIF 188
            :..|..|...|:.|.|:|..   ..:.|.:...|.|.....|:.|:.......|:.|.:  ..:.
Zfish   139 KRKRKVLAKVFSRGALEAYL---TRLQDVVKSEIAKWCTETGSVEVYTAAKSLTFRIAV--RVLL 198

  Fly   189 GLDVDSFADPNNEFQIISKKVNR--NN-----IEDIIRG------TSSFLYPGLEKFFVKIGWKQ 240
            ||.::     ..:...:||...:  ||     |:..:.|      ....|:..:||...:...||
Zfish   199 GLHLE-----EQQITYLSKTFEQLMNNLFSLPIDTPVSGLRKGIRAREILHSAMEKIIEEKLKKQ 258

  Fly   241 EATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIA 305
            :|::............||.:                            .|.|...:|..:.:||
Zfish   259 QASDYCDAFDYMLSSAREND----------------------------YELTMQELKETAVELI- 294

  Fly   306 GQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAK----------------------------- 341
                   .|.:.||||.::..:.:|.::|:|.|:|:
Zfish   295 -------FAAHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHCRSRCNGNAISEEG 352

  Fly   342 -------EDVRSAIEK-----------------HGGKLTYDAISDMKYLEACILETARKYPAL-- 380
                   .|.||||.|                 |...|:.:.:|.:.||:..:.|..|..|.:
Zfish   353 EAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSG 417

  Fly   381 ---PLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGKDYTQA- 441
               .:|.......|.:|       ||..::.|:...|...|.:.:|..:.|:|:.. |::.:::
Zfish   418 GYRTVLQTFELNGYQIP-------KGWSVMYSIRDTHETAEAYQNPELFDPDRFCV-GREESKSE 474

  Fly   442 --AYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVY----GIPLM-PKSG 499
              :|:|||.|.|.|||..:..:.:|....::|:..|       |.:....|    .:|:: |.:|
Zfish   475 RFSYVPFGGGVRRCIGRELALIVLKTLAVELLATAD-------CTLATQTYPRMQTVPIVHPVNG 532

  Fly   500 VPV 502
            :.|
Zfish   533 LHV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	98/523 (19%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	102/547 (19%)