Protein Alignment Cyp6d5 and CYP2W1

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_011513742.1
• Gene: CYP2W1 / 54905
• HGNCID: 20243
• Length: 564
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 95/436 - (21%)
• Similarity: 179/436 - (41%)
• Gaps: 75/436 - (17%)

  Fly    66 PVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQMEGASWRALRNKL 130
            ||..::|..:..:::...:...:.|........||......:.......:|...||.|||.|
Human    65 PVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAAR--- 126

  Fly   131 TPSFTSGKLKAMFETSDSVGDKLVDSIR---KQLPANGAKELELKKLMATYAIDIIATTIFGLDV 192
              .||...|.::....:.|.||::..::   .||.....:...| .|:.....:|....:||...
Human   127 --QFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPL-ALLGWAPSNITFALLFGRRF 188

  Fly   193 DSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERMRELSNRTVDLR 257
            | :.||     :....:...:...::.|:     |||:.|.| ..|.....:..|.:..:..::|
Human   189 D-YRDP-----VFVSLLGLIDEVMVLLGS-----PGLQLFNV-YPWLGALLQLHRPVLRKIEEVR 241

  Fly   258 EQNNIVRKDLLQLLLQLR------------------NQGKINTDDNIWSAESTKNGVKSMSKDLI 304
            .        :|:.||:.|                  .||:.:..:.:: ||:  |.| :.:.|::
Human   242 A--------ILRTLLEARRPHVCPGDPVCSYVDALIQQGQGDDPEGLF-AEA--NAV-ACTLDMV 294

  Fly   305 AGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISD---MKYL 366
                    :||.|||::|..:....:.::|:|..:.:|::...:    |......:.|   :.|.
Human   295 --------MAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVL----GPGRTPRLEDQQALPYT 347

  Fly   367 EACILETARKYPALPLLNRICTKDYPVPDSKL---VIQKGTPIIISLIGMHRDEEYFPDPLAYKP 428
            .|.:.|..|....||.:.| ||    ..|::|   ::.||||:|..|..:..||..:..|..:.|
Human   348 SAVLHEVQRFITLLPHVPR-CT----AADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNP 407

  Fly   429 ERYLE-NGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSN 473
            ..:|: ||....:.|:|||..|.|:|:|.|:.:..:.:..|.:|.:
Human   408 GHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	95/436 (22%)
CYP2W1	XP_011513742.1	cytochrome_P450	63..459	CDD:477761	95/436 (22%)