Protein Alignment Cyp6d5 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 152/521 - (29%)
• Similarity: 256/521 - (49%)
• Gaps: 67/521 - (12%)

  Fly     5 YLLIAAV-TLLYVYLKWTFSYWDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPV 67
            :||:|.: .|.|.:...|...:.::|.|.. ..:|| |.:.:..:|...|.|   :.||...: :
  Rat    12 WLLLAIILVLFYRFGTRTHGIFKKQGIPGP-KPLPFLGTVLNYYRGLWKFDM---ECYKKCGK-I 71

  Fly    68 IGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKN-DP---MSASLFQMEGASWRALRN 128
            .||:....|...:.|.::...||||:..|     |:.:.:| .|   ||.|:...:...|:..|.
  Rat    72 WGLFDGQTPVFAIMDTEMIKSVLVKECFS-----VFTNRRNIGPVGIMSKSISVAKDEEWKRYRA 131

  Fly   129 KLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVD 193
            .|:|:||||:||.||...:..||.||..:::::  ...|.|.:|::...|::|:|.:|.|.::::
  Rat   132 FLSPTFTSGRLKEMFPIIEHYGDILVKYLKQKV--EKGKPLAMKEVFGAYSMDVITSTSFEVNIN 194

  Fly   194 SFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFV----------KIGWKQEATERMRE 248
            |..:|.:.|....||..|.:..|.: ..|..|:|.|...:.          .:.:.|:...||::
  Rat   195 SINNPKDPFVEKVKKFQRFDFFDPL-FLSVVLFPFLTPIYEMLNICLFPKDSVAFFQKFVYRMKQ 258

  Fly   249 LSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYV 313
               ..:|.:.::   |.|.|||::...|..|            .|...|::|...|..|..:|..
  Rat   259 ---TRLDSKHKH---RVDFLQLMMNAHNNSK------------DKVSHKALSDIEIVAQAIIFIF 305

  Fly   314 AGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYP 378
            |.||||:||.||.||.|..:|:..:|.:|::..|:...... |||.:.:|:||:..:.||.|.||
  Rat   306 ASYETTSSTLSFVLYSLATHPDSQKKLQEEIDRALPNKAPP-TYDTVMEMEYLDMVLNETPRLYP 369

  Fly   379 ALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-LENGKDYTQAA 442
            ....|.|:|.||..:  ..:.|.||:.::|....:..|.:::|:|..:.|||: .||........
  Rat   370 IGYRLERVCKKDIKL--DGVFIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKENKGSIDPYV 432

  Fly   443 YLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLSLK 507
            |||||.|||.|||.|...:|:|:|:.|||.||..::    ||            ::.:|::||.:
  Rat   433 YLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQL----CE------------ETQIPLKLSRQ 481

  Fly   508 K 508
            :
  Rat   482 R 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	133/452 (29%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	136/462 (29%)