Protein Alignment Cyp6d5 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 107/548 - (19%)
• Similarity: 210/548 - (38%)
• Gaps: 159/548 - (29%)

  Fly     2 IGIYLLIAAVTLLYVYLKWTFSYWDRKGFPSTG-VSIPFGALESVTKGKRSFGMA---------- 55
            :|..:|:.....|.:.|....|.|..:.||||| ..:.:|          .:|.|
Mosquito    10 LGTTVLLTGAFGLCLILDKRRSLWVDRRFPSTGRTCVLYG----------DYGAAGRTEHRIYTT 64

  Fly    56 --IYDMYKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQM 118
              :|..:||.|.|:.|..:.|.|.::..|..|...:|.::|..        ::|:....:|:|:
Mosquito    65 QRLYREFKSKKWPIGGALMYLTPCVIPTDPHLIEFLLNEEFGK--------NKKSSIAGSSIFR- 120

  Fly   119 EGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDII 183
                      |...||......::...:....:|:|:.:     ....:.:::|.:...||:.:|
Mosquito   121 ----------KRWSSFEDEHYNSLVNVATEESEKVVEML-----CTSKQPVDVKVIAELYAVRMI 170

  Fly   184 ATTIFG------------------------LDVDSFADPNNEFQIISKKV------NRNNIEDII 218
            |..:||                        .||.|.|.|:..|....:|:      :...:::::
Mosquito   171 ARCVFGKRCTEESHTFPITEKLASQPGGIVWDVFSTAFPSTTFTATLRKLLDHFQKHPALLDELV 235

  Fly   219 RGTSSFLYPGLEKFFVKIGWKQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTD 283
               |||                        |:.||.|:         :.||.|.:...:.|.|
Mosquito   236 ---SSF------------------------LTERTADV---------NFLQHLKRTEQRAKAN-- 262

  Fly   284 DNIWSAESTKNG-VKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSA 347
                  |....| .:::..:|:..   :|:||     :.|....|:|:..|.::.:...|.:
Mosquito   263 ------ERIAFGDTRALMLELVQN---VFFVA-----SGTIIACLFEMGHNGDIQKGLHETL--- 310

  Fly   348 IEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIG 412
              :.......|.      ||..|.||.||||.:..::.:...:..:|..:||:.|.|.:::.:..
Mosquito   311 --QRSNPFAVDT------LENVISETLRKYPPVGEISFVTVANNRLPSGELVVPKNTRVVVPIYA 367

  Fly   413 MHRDEEYFPDPLAYKPERYLENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLE 477
            :..|.|::|||..:.|:|.:.:..:.: ..|.|.|..| :.||:.:..:.|::|::.:|.
Mosquito   368 LQHDAEHYPDPERFNPKRSIFSSSEQS-VLYRPLGVQP-LPIGSSLALLMVRVALSNILG----- 425

  Fly   478 IRKEKCEIEFGVYGIPLMPKSGVPVRLS 505
                :|.:.       |.|:|...:::|
Mosquito   426 ----RCTVR-------LTPESPATLKIS 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	89/468 (19%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	90/474 (19%)