DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6d5 and sad

DIOPT Version :9

Sequence 1:	NP_650327.1	Gene:	Cyp6d5 / 41706	FlyBaseID:	FBgn0038194	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_650123.1	Gene:	sad / 44858	FlyBaseID:	FBgn0003312	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	107/513 - (20%)
Similarity:	186/513 - (36%)	Gaps:	140/513 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KGFPSTGVSIPFGALESVT-------KGKRSFGMAIYDMYKSTKEPVIGLYLTLRPALLVRDAQL 85
            ||.|..|..:...|....|       ...:.:|....:....|::           |:.|..|.|
  Fly    63 KGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQD-----------AVFVSSANL 116

  Fly    86 AHDVLVKDFASFHDRGVYVDEKNDPM----------------SASLFQMEGASWRALRNKLTPSF 134
            .             |||:..|...|.                ...||.||||.|...|..|....
  Fly   117 M-------------RGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLL 168

  Fly   135 TSGKLKAMFETSDSVGDKLVDSIRKQ------LPANGAKELE------LKKLMATYAIDIIATTI 187
            .:|.|..|....:|...::||..:::      :|...:.|:.      |::.:..::|:::...:
  Fly   169 LNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIM 233

  Fly   188 FGLDV----------DSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLY--PGLEKFFVKIGWKQ 240
            ||..|          |.|.      ||:.|         :...:|..:.  |.|.:......|:.
  Fly   234 FGTSVLTCPKIQSSLDYFT------QIVHK---------VFEHSSRLMTFPPRLAQILRLPIWRD 283

  Fly   241 -EAT--ERMRE---LSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSM 299
             ||.  |.:||   :.:..:.::|.......:.|...||              :|:...:.:|.:
  Fly   284 FEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHRLQ--------------AADVPGDMIKRI 334

  Fly   300 SKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEK-AKEDVRSAIEKHGGKLTYDAISDM 363
            ..||:        :|..:|||.::.:.|:.|::.|.:.:: |||               .|.:|.
  Fly   335 FVDLV--------IAAGDTTAFSSQWALFALSKEPRLQQRLAKE---------------RATNDS 376

  Fly   364 KYLEACILETARKYPALPLLNRICTKDYPVPDSKL---VIQKGTPIIISLIGMHRDEEYFPDPLA 425
            :.:...|.|:.|.||..|.:.|     |...|::|   .|:|.|.:::||....||..:|..|..
  Fly   377 RLMHGLIKESLRLYPVAPFIGR-----YLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPER 436

  Fly   426 YKPERYL--ENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKE 481
            ..|||:.  |..:.:.....|||..|.|.|||.|:....:...:.:..:.|::....|
  Fly   437 VLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	98/463 (21%)
sad	NP_650123.1	p450	63..497	CDD:299894	107/513 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910