Protein Alignment Cyp6d5 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 152/535 - (28%)
• Similarity: 256/535 - (47%)
• Gaps: 77/535 - (14%)

  Fly     6 LLIAAVT-LLYVYL--KWTFSYWDRKGFPSTGVSIPFGALESVTKGKRSFGM-AIYDMYKSTKE- 65
            :|::.|: ::||.|  |..|....:.|..........|.|:.:.:.|...|. ..||.|....:
 Worm     9 ILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYNKLHKQ 73

  Fly    66 --PVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQMEGAS-WRALR 127
              ...|:|...:..:.:.:.:...:|.:|:|::|.||......:::.:..||.|....| |:..|
 Worm    74 FGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTYESGWKHTR 138

  Fly   128 NKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDV 192
            :.:.|.|::||:|||.||..|..|..::.::::  |:..::.::........:|:|....|.:|.
 Worm   139 SAIAPIFSTGKMKAMHETIHSKVDLFLEILKEK--ASSGQKWDIYDDFQGLTLDVIGKCAFAIDS 201

  Fly   193 DSFADPNNEFQIISKKVNRN---NIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERMRELSNRTV 254
            :...|.|:.|.:.::|...|   ....||  ::|||:|.|.|.     ||  ...|..:|:...:
 Worm   202 NCQRDRNDVFYVNARKFITNIDIRHSKII--STSFLFPELSKL-----WK--VLYRFTDLAKAEI 257

  Fly   255 DLREQNNIVRK-----------DLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQL 308
            .|.|....|.:           |||:|||        |.:|:       |:  |.|:|..:....
 Worm   258 PLVEGLADVYERRRGGEGSDSVDLLKLLL--------NREDD-------KS--KPMTKQEVIENC 305

  Fly   309 FLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILET 373
            |.|.:||||||::..::..|.|::.|.|.:|..|::..|  |..|.||||:|.:||||:....||
 Worm   306 FAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDYVYKET 368

  Fly   374 ARKYPALPLL---NRICTKD-------YPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKP 428
            .|.||  |::   ||.|.||       ||         ||..::.....:||:.|.:..|..:.|
 Worm   369 LRCYP--PVIHFSNRRCLKDITIRGQFYP---------KGAIVVCLPHTVHRNPENWDSPEEFHP 422

  Fly   429 ERYLENGKDYTQA-AYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGI 492
            ||: ||.::.:.: .::|||.|||.|:|.|..::..|..|||:|..|:|:..:.:.::.....|:
 Worm   423 ERF-ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELKQFEGEADLIPDCNGV 486

  Fly   493 PLMPKSGVPVRLSLK 507
            .:.||.  ||||.||
 Worm   487 IMRPKD--PVRLHLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	131/466 (28%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	132/465 (28%)