Protein Alignment Cyp6d5 and Cyp3a2

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_063127162.1
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 159/520 - (30%)
• Similarity: 255/520 - (49%)
• Gaps: 73/520 - (14%)

  Fly     7 LIAAVTLLYVYLKWTFSY--WDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPVI 68
            ::.||.|:.:|...|..:  :.::|.|.. ..:|| |.:.:..||...|.|..|..|..    :.
  Rat    13 VLLAVILVLLYRLGTHRHGIFKKQGIPGP-KPLPFLGTVLNYYKGLGRFDMECYKKYGK----IW 72

  Fly    69 GLYLTLRPALLVRDAQLAHDVLVKD-FASFHDR------GVYVDEKNDPMSASLFQMEGASWRAL 126
            ||:....|...:.|.::..:||||: |:.|.:|      |:        |..::...:...|:..
  Rat    73 GLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGI--------MGKAVSVAKDEEWKRY 129

  Fly   127 RNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLD 191
            |..|:|:||||:||.||...:..||.||..::::  |...|.:.:||:...|::|:|.:|.||::
  Rat   130 RALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQE--AETGKPVTMKKVFGAYSMDVITSTSFGVN 192

  Fly   192 VDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFV----------KIGWKQEATERM 246
            |||..:|.:.|...:||:.|.:..|.: ..|..|:|.|...:.          .|.:.|:...|:
  Rat   193 VDSLNNPKDPFVEKTKKLLRFDFFDPL-FLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKFVHRI 256

  Fly   247 RELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLF 311
            :|     ..|..::.:.|.|.|||:|...|    |:.|.:        ..|::|...|..|..:|
  Rat   257 KE-----TRLDSKHKVHRVDFLQLMLNAHN----NSKDEV--------SHKALSDVEIIAQSVIF 304

  Fly   312 YVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARK 376
            ..||||||:||.||.||.|..:|::.:|.:|::..|:...... |||.:.:|:||:..:.||.|.
  Rat   305 IFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPP-TYDIVMEMEYLDMVLNETLRL 368

  Fly   377 YPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-LENGKDYTQ 440
            ||....|.|:|.||..:  ..|.|.||:.:.|....:|.|.:::|.|..:.|||: .||......
  Rat   369 YPIGNRLERVCKKDIEL--DGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDP 431

  Fly   441 AAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLS 505
            ..|||||.|||.|||.|...:|:|:|:.|||.||..:..||                :.:|::||
  Rat   432 YVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKE----------------TQIPLKLS 480

  Fly   506  505
              Rat   481  480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	140/455 (31%)
Cyp3a2	XP_063127162.1	None