Protein Alignment Cyp6d5 and Cyp51

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 106/543 - (19%)
• Similarity: 192/543 - (35%)
• Gaps: 159/543 - (29%)

  Fly     1 MIGIYLLIAAVTLLYVYL------------------KWTFSYWDRKGFPSTGVSIPFGALESVTK 47
            ::...|:..|.||..|||                  .:.:|     ..|..|.:|.||      |
  Rat    26 LLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYS-----PIPFLGHAIAFG------K 79

  Fly    48 GKRSFGMAIYDMYKSTKEPV-----IGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEK 107
            ....|....|:.|    .||     :|...|.   ||..||                ..:..:.|
  Rat    80 SPIEFLENAYEKY----GPVFSFTMVGKTFTY---LLGSDA----------------AALLFNSK 121

  Fly   108 NDPMSASLFQMEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELK 172
            |:.::|.  ::.|       ...||.|..|                   :...:|  .|..||.|
  Rat   122 NEDLNAE--EVYG-------RLTTPVFGKG-------------------VAYDVP--NAVFLEQK 156

  Fly   173 KLMATYAIDIIATTIFGLDVDSF--------------------ADPNNEFQIISKKV-------- 209
            |::.:           ||::..|                    :...|.|:.:|:.:
  Rat   157 KILKS-----------GLNIAHFKQYVSIIEKEAKEYFKSWGESGERNVFEALSELIILTASHCL 210

  Fly   210 NRNNIEDIIRGTSSFLYPGLEKFFVKIGW-------------KQEATERMRELSNRTVDLREQNN 261
            :...|...:....:.||..|:..|....|             :..|...::.:..:.:..|..:.
  Rat   211 HGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSK 275

  Fly   262 IVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFT 326
            ...:|:||.||                 :||....:.::.|.|||.|....:||..|:::|:::.
  Rat   276 EPAEDILQTLL-----------------DSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWM 323

  Fly   327 LYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDY 391
            .:.|.::..:.:|...:.::...:....|||:.:.|:..|:.||.||.|..|  |::..:.....
  Rat   324 GFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDLNLLDRCIKETLRLRP--PIMTMMRMAKT 386

  Fly   392 PVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYL-ENGKDYTQAAYLPFGEGPRMCIG 455
            |...:...|..|..:.:|.....|.::.:.:.|.:.|:||| :|.....:.||:|||.|...|||
  Rat   387 PQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIG 451

  Fly   456 ARMGKVNVKIAIAKVLSNFDLEI 478
            .....|.:|...:.:|..::.::
  Rat   452 ENFAYVQIKTIWSTMLRLYEFDL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	89/463 (19%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	91/470 (19%)