Protein Alignment Cyp6d5 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 144/567 - (25%)
• Similarity: 242/567 - (42%)
• Gaps: 114/567 - (20%)

  Fly     3 GIYLLIAAVTLLYVYLKW----TFSYWDRKGF----PSTGVSIPF-GALESVTKGKRSFGMAIYD 58
            |..:.:....:|...|||    .||...:.|.    ||     || |.|....:|.....:.:.:
  Rat    13 GTVVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPS-----PFVGNLMFFRQGFWESHLELRE 72

  Fly    59 MYKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDR---GVYVDEKNDP--MSASLFQM 118
            .|    .|:.|.||..|..:::.|..:..:|||::|::|.:|   |:      :|  ::.|:..:
  Rat    73 RY----GPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGL------EPKLIADSVLML 127

  Fly   119 EGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDII 183
            ....|..:|..|..:|:..||..|........:.|:..::....:..|  .::::....:..:::
  Rat   128 RDRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDA--FDIQRCYCCFTTNVV 190

  Fly   184 ATTIFGLDVDSFADPNNEFQIISKKV----NRNNIEDIIRGTSSFLYP-----------GLEKFF 233
            |:..||::|:|...|.:.|....::|    ....:..:|....|.:.|           .|..||
  Rat   191 ASVAFGIEVNSQDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARILPNKNRDELNGFF 255

  Fly   234 -------VKIGWKQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQL-RNQGKINTD--DNIWS 288
                   :.:..||.|.||                  |.|.||::|.. |:...:..:  |.:..
  Rat   256 NTLIRNVIALRDKQTAEER------------------RGDFLQMVLDAQRSMSSVGVEAFDMVTE 302

  Fly   289 AEST-------------KNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKA 340
            |.|:             .:..|.::.|.||||.|||.:||:|.|.:|.||..|.|..:||..|:.
  Rat   303 ALSSAECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERL 367

  Fly   341 KEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTP 405
            .::|...:|||......:....:.||:..:.||.|.||......|...:|..|....  |..|:.
  Rat   368 LKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQH--IPAGSV 430

  Fly   406 IIISLIGMHRDEEYFPDPLAYKPERYLENG----KDYTQAAYLPFGEGPRMCIGARMGKVNVKIA 466
            :.|::..:|.|.|::|:|..:.|||:....    |.:|   |||||.|||.|:|.|:|.:.||:.
  Rat   431 LEIAVGALHHDPEHWPNPETFDPERFTAEARLQQKPFT---YLPFGAGPRSCLGVRLGLLVVKLT 492

  Fly   467 IAKVLSNFDLEIRKEKC-EIEFGVYGIPLM--------PKSGVPVRL 504
            :.:||..|    |.|.| |.:     :||.        ||:||.|::
  Rat   493 LLQVLHKF----RFEACPETQ-----VPLQLESKSALCPKNGVYVKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	126/493 (26%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	127/496 (26%)