Protein Alignment Cyp6d5 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 149/542 - (27%)
• Similarity: 258/542 - (47%)
• Gaps: 86/542 - (15%)

  Fly     6 LLIAAVTLLYVYLKWTFSYWDRKGF---PSTGVSIP-----FGALESVTKGKRSFGMAIYD---- 58
            |::.::.:|.|.......:..|:.|   ...|::.|     .|.|:.:...|...|   ||
 Worm     4 LILTSILILLVSFIIYILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDRKEKLG---YDDSNK 65

  Fly    59 ----MYKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQME 119
                ::|...| ..|:|...:..:::.:.:...:|.:|:|::|.||.|.....::.::.||.|..
 Worm    66 WFNELHKQYGE-TFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNT 129

  Fly   120 GAS-WRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDII 183
            .|: |:..|:.:.|.|::||:|||.||..|..|..:|.:|::  |:..::.::.:......:|:|
 Worm   130 YATGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREK--ASSGQKWDIYEDFQGLTLDVI 192

  Fly   184 ATTIFGLDVDSFADPNNEFQIISKKVNRNNIEDIIRG---TSSFLYPGLEKFFVKIGWKQEATER 245
            ....|.:|.:...|.|:.|.:.::|...|  .||...   .:||:.|.|...     |:  |..:
 Worm   193 GKCAFAIDSNCQRDRNDVFYVNARKFIAN--IDIRHSKVIAASFILPELAPL-----WR--ALYK 248

  Fly   246 MRELSNRTVDLRE-QNNIVRK----------DLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSM 299
            ...|::..:.|.| .:|:..:          |||:|||        |.:|:       |:  |.|
 Worm   249 YTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLL--------NREDD-------KS--KPM 296

  Fly   300 SKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMK 364
            :|..:....|.|.:||||||::..::..|.|::.|.|.:|..|::..|  |..|.||||:|.:||
 Worm   297 TKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMK 359

  Fly   365 YLEACILETARKY-PALPLLNRICTKD-------YPVPDSKLVIQKGTPIIISLIGMHRDEEYFP 421
            ||:....||.|.| |.:..:||.|..|       ||         ||:.:......:|.:.|.:.
 Worm   360 YLDYVYKETLRCYPPVIHFINRRCLADITIRGQFYP---------KGSVVTCLPHTVHLNPENWD 415

  Fly   422 DPLAYKPERYLENGKDYTQA-AYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEI 485
            .|..:.|||: ||.::.:.: .::|||.|||.|:|.|..::..|..|.|:|..|:|:..|.:.::
 Worm   416 SPEEFHPERF-ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFKGEADL 479

  Fly   486 EFGVYGIPLMPKSGVPVRLSLK 507
            .....|:.:.||.  ||||.||
 Worm   480 IPDCNGVIMRPKD--PVRLLLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	129/461 (28%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	130/464 (28%)