Protein Alignment Cyp6d5 and Cyp51

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 533
• Identity: 109/533 - (20%)
• Similarity: 194/533 - (36%)
• Gaps: 139/533 - (26%)

  Fly     1 MIGIYLLIAAVTLLYVYLKWTFSYWDRKGFPSTGVS-------IPF-GALESVTKGKRSFGMAIY 57
            ::...|:..|.||..||| :..:.......|:...|       ||| |...:..|....|....|
Mouse    26 LLSTLLIACAFTLSLVYL-FRLAVGHMVQLPAGAKSPPHIYSPIPFLGHAIAFGKSPIEFLENAY 89

  Fly    58 DMYKSTKEPV-----IGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQ 117
            :.|    .||     :|...|.   ||..||                ..:..:.||:.::|.  :
Mouse    90 EKY----GPVFSFTMVGKTFTY---LLGSDA----------------AALLFNSKNEDLNAE--E 129

  Fly   118 MEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDI 182
            :.|       ...||.|..|                   :...:|  .|..||.||::.:
Mouse   130 VYG-------RLTTPVFGKG-------------------VAYDVP--NAIFLEQKKIIKS----- 161

  Fly   183 IATTIFGLDVDSF--------ADPNNEFQIISKKVNRNNIE---DIIRGTSSF------------ 224
                  ||::..|        .:....||...:...||..|   ::|..|:|.
Mouse   162 ------GLNIAHFKQYVPIIEKEAKEYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLN 220

  Fly   225 -----LYPGLEKFFVKIGW-------------KQEATERMRELSNRTVDLREQNNIVRKDLLQLL 271
                 ||..|:..|....|             :..|...::.:..:.:..|..:....:|:||.|
Mouse   221 EKVAQLYADLDGGFTHAAWLLPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTL 285

  Fly   272 LQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEV 336
            |                 :||....:.::.:.|:|.|....:||..|:::|:::..:.|.::..:
Mouse   286 L-----------------DSTYKDGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPL 333

  Fly   337 MEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQ 401
            .||...:.::...:....||||.:.|:..|:.||.||.|..|  |::..:.....|...:...|.
Mouse   334 QEKCYLEQKAVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRP--PIMTMMRMAKTPQTVAGYTIP 396

  Fly   402 KGTPIIISLIGMHRDEEYFPDPLAYKPERYL-ENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKI 465
            .|..:.:|.....|.::.:.:.|.:.|:||| :|.....:.||:|||.|...|:|.....|.:|.
Mouse   397 PGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKT 461

  Fly   466 AIAKVLSNFDLEI 478
            ..:.:|..::.::
Mouse   462 IWSTMLRLYEFDL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	92/463 (20%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	94/470 (20%)