Protein Alignment Cyp6d5 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 527
• Identity: 164/527 - (31%)
• Similarity: 262/527 - (49%)
• Gaps: 84/527 - (15%)

  Fly     4 IYLLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPV 67
            :.||...:.|||.|...|...:.::|.|.. ..:|| |.:.:..||...|.|..|:.|..|
Mouse    12 LVLLAIILVLLYRYGTCTHGLFKKQGIPGP-KPLPFLGTVLNYYKGLWKFDMECYEKYGKT---- 71

  Fly    68 IGLYLTLRPALLVRDAQLAHDVLVKD-FASFHDR------GVYVDEKNDPMSASLFQMEGASWRA 125
            .||:....|..::.|.:...:||||: |:.|.:|      |:        ||.|:...:...|:.
Mouse    72 WGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGI--------MSKSISLAKDEEWKR 128

  Fly   126 LRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGL 190
            .|..|:|:||||.||.||...:..||.||..:|::  |...|.:.:|.::..|::|:|.:|.||:
Mouse   129 YRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQE--AEKGKPVAVKDVLGAYSMDVIISTTFGV 191

  Fly   191 DVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLE----------------KFFVKIGWK 239
            ::||..:|.:.|...:|||.|.:..|.: ..|..|:|.|.                :||.|.
Mouse   192 NIDSLNNPEDPFVENAKKVLRFDYFDPL-SLSVALFPFLTPIYEMLNICMFPKDSIEFFKKF--- 252

  Fly   240 QEATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLI 304
               .:||.|  || :|.::::   |.|.:.|:::..|:.|            .|:..|::|:..|
Mouse   253 ---VDRMTE--NR-LDSKQKH---RVDFIYLMMEAYNKSK------------DKDSHKALSEIEI 296

  Fly   305 AGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEAC 369
            ..|..:|..||||||:|..|||:|.|..:|::.:|.:|::..|:...... |||.:..|:||:..
Mouse   297 TAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPP-TYDTVMAMEYLDMV 360

  Fly   370 ILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-LE 433
            :.||.|.||....|.|:|.||..:  :.:.|.||:.:||....:|.|.:::|:|..::|||: .|
Mouse   361 LNETLRLYPITNRLQRVCKKDVEI--NGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKE 423

  Fly   434 NGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKS 498
            |........|||||.|||.|||.|...:|:|:|:.|||.||..:..||                :
Mouse   424 NKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKE----------------T 472

  Fly   499 GVPVRLS 505
            .:|::||
Mouse   473 QIPLKLS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	143/461 (31%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	147/471 (31%)