Protein Alignment Cyp6d5 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 519
• Identity: 157/519 - (30%)
• Similarity: 257/519 - (49%)
• Gaps: 73/519 - (14%)

  Fly     6 LLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPVIG 69
            ||..::.|||:|...:...:.:.|.|.. ..:|| |.:.:..||.....:..:..|..    :.|
Mouse    14 LLATSLVLLYLYGTHSHGIFKKLGIPGP-KPLPFLGTILAYQKGFWECDIQCHKKYGK----MWG 73

  Fly    70 LYLTLRPALLVRDAQLAHDVLVKD-FASFHDR------GVYVDEKNDPMSASLFQMEGASWRALR 127
            ||...:|.|.:.|..:...||||: :::|.:|      |:        :..::...|...|:.:|
Mouse    74 LYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGI--------LKKAISISENEEWKRIR 130

  Fly   128 NKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDV 192
            ..|:|:||||:||.||...:...|.||.::|:.|  ...|...:|.:...|::|:|..|.||:::
Mouse   131 ALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGL--GEGKPTSMKDIFGAYSMDVITATSFGVNI 193

  Fly   193 DSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVK----------IGWKQEATERMR 247
            ||..:|.:.|....||:.:.:|.|.: ..|..|:|.|...|..          |.:...:.|||:
Mouse   194 DSLNNPQDPFVEKIKKLLKFDIFDPL-FLSVTLFPFLTPVFDALNVSLFPRDVISFFTTSVERMK 257

  Fly   248 ELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFY 312
            |  ||..:..:|    |.|.|||::..:|.             .||...|::|...|..|..:|.
Mouse   258 E--NRMKEKEKQ----RVDFLQLMINSQNY-------------KTKESHKALSDVEIVAQSVIFI 303

  Fly   313 VAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKY 377
            .||||||:|..||.||.|..:|:|.:|.::::.:|: .:....|||.:..|:||:..:.||.|.|
Mouse   304 FAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRLY 367

  Fly   378 PALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGKD-YTQA 441
            |....|.|:|..|..:  :.|.|.|||.::|....:|:|.:|:|:|..::|||:.:..:| ....
Mouse   368 PIAGRLERVCKTDVEI--NGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPY 430

  Fly   442 AYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLS 505
            .|||||.|||.|||.|...:|:|:|:.:||.||.::..||                :.:|::||
Mouse   431 MYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKE----------------TEIPLKLS 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	140/455 (31%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	144/465 (31%)