Protein Alignment Cyp6d5 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 513
• Identity: 157/513 - (30%)
• Similarity: 257/513 - (50%)
• Gaps: 60/513 - (11%)

  Fly     6 LLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPVIG 69
            ||...:.|||.|...|...:.::|.|.. ..:|| |.:.:..||...|.|..|:.|..|    .|
Mouse    14 LLAIILVLLYRYGTRTHGLFKKQGIPGP-KPLPFLGTVLNYYKGLWKFDMECYEKYGKT----WG 73

  Fly    70 LYLTLRPALLVRDAQLAHDVLVKD-FASFHDR------GVYVDEKNDPMSASLFQMEGASWRALR 127
            |:....|..::.|.::..:||||: |:.|.:|      |:        ||.::...:...|:..|
Mouse    74 LFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGI--------MSKAISISKDEEWKRYR 130

  Fly   128 NKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDV 192
            ..|:|:|||||||.||...:..||.||..:.::  |...|.:.:|.::..|:||:|.:|.||::|
Mouse   131 ALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQE--AEKGKPVTMKDVLGAYSIDVITSTSFGVNV 193

  Fly   193 DSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIG---WKQEATERMRELSNRTV 254
            ||..:|.:.|...:|.:.|.:..|.: ..|..|:|.|...:..:.   :.:::.|..::..||..
Mouse   194 DSLNNPEDPFVEKAKGILRVDFFDPL-VFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMK 257

  Fly   255 DLR-EQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYET 318
            :.| :.....|.|.|||::...|..|            .|:..|::|...|..|..:|..|||||
Mouse   258 ESRLDSKQKHRVDFLQLMMNAHNNSK------------DKDSHKALSDMEITAQSIVFIFAGYET 310

  Fly   319 TASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYPALPLL 383
            |:||.|||||.|..:|::.:|.:|::...:...... |||.:.:|:||:..:.||.|.||....|
Mouse   311 TSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPP-TYDTVMEMEYLDMVLNETLRLYPIGNRL 374

  Fly   384 NRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-LENGKDYTQAAYLPFG 447
            .|.|.||  |..:.:.|.||:.::|....:|.|.:::|:|..::|||: .||........|:|||
Mouse   375 ERFCKKD--VELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFG 437

  Fly   448 EGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLS 505
            .|||.|||.|...:.:|:|:.||:.||..    :.|:            ::.:|::||
Mouse   438 IGPRNCIGMRFAFMTMKLALTKVMQNFSF----QPCQ------------ETQIPLKLS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	136/449 (30%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	140/459 (31%)