Protein Alignment Cyp6d5 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 156/523 - (29%)
• Similarity: 258/523 - (49%)
• Gaps: 70/523 - (13%)

  Fly     6 LLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPF-GALESVTKGKRSFGMAIYDMYKSTKEPVIG 69
            ||:..:|||..|..|.:..:.|.|.|.. ..||| |.......|...|.|..:..|..    |.|
 Frog    14 LLVLLLTLLAYYAIWPYKLFKRYGIPGP-TPIPFIGTFLGNRHGLMEFDMECFKKYGK----VWG 73

  Fly    70 LYLTLRPALLVRDAQLAHDVLVKD----FASFHDRGVYVDEKNDPMSASLFQMEGASWRALRNKL 130
            :|...:|.|.:.|..:...::||:    |.:..|.|:     :.|:.:|:...:...|:.:|..|
 Frog    74 IYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGL-----SGPLKSSVLISKDEQWKRIRTVL 133

  Fly   131 TPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVDSF 195
            :|:|||||||.||...:..|:.||.:|.|::  |..:.|::|.:..:|::||:.:|.|.::|||.
 Frog   134 SPTFTSGKLKQMFPLMNHYGELLVKNIHKKI--NNKEPLDMKHIFGSYSMDIVLSTSFSVNVDSM 196

  Fly   196 ADPNNEFQIISKKVNRNNIED--------IIRGTSSFLYPGLEKF---FVK---IGWKQEATERM 246
            .:||:.|     ..|..|:..        :|.....||.|.|:|.   |:.   :.:.::|...:
 Frog   197 NNPNDPF-----VTNARNLFTFSFFNPLFLISILCPFLVPLLDKMNFCFLSLKILNFFKDAVASI 256

  Fly   247 RELSNRTVDLREQNNIVRKDLLQLLLQLR-NQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFL 310
            ::  .|.....|.    |.|.|||::..: |:||.       ..|..|:|.|.:|...|..|..:
 Frog   257 KK--KRQKGTHED----RVDFLQLMVDAQSNEGKS-------VPEEEKHGYKELSDTEILAQSLI 308

  Fly   311 FYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETAR 375
            |.:||||||::|..|..|.:..:|:|..|.:|:: .|:..:....||||:..|:|::..|.|:.|
 Frog   309 FIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEI-DALLPNKAPPTYDALMKMEYMDMVINESLR 372

  Fly   376 KYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERY-LENGKDYT 439
            .:|....::|:|.|...:  :.:.|..|..|::.|..:|.:.|.:|:|..::|||: .||.|:..
 Frog   373 MFPPAIRIDRVCKKTMEI--NGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQD 435

  Fly   440 QAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRL 504
            ...:||||.|||.|||.|...||:|:|:..:|.||.||..|:                :.||:::
 Frog   436 PYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKD----------------TPVPLKI 484

  Fly   505 SLK 507
            ..|
 Frog   485 CTK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	135/457 (30%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	139/469 (30%)