Protein Alignment rdx and Rhobtb3

DIOPT Version :10

• Sequence 1: NP_650326.3
• Gene: rdx / 41704
• FlyBaseID: FBgn0264493
• Length: 829
• Species: Drosophila melanogaster
• Sequence 2: NP_082769.1
• Gene: Rhobtb3 / 73296
• MGIID: 1920546
• Length: 611
• Species: Mus musculus
• Alignment Length: 488
• Identity: 103/488 - (21%)
• Similarity: 159/488 - (32%)
• Gaps: 167/488 - (34%)

  Fly   397 NQQQPQQSPLCLVLLVKCPNSKE--------------------------FCNAAANFCDKRLPVN 435
            |::.|...|||......|..:.|                          |......|..:.|...
Mouse   138 NEELPCTCPLCTSDRGSCVTTTEGIQLAKELGATYLELHSLDDFYIGKYFGGVLEYFMIQALNQK 202

  Fly   436 ECQASQTARVTSNLHASSSTMAVSRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCR 500
            ..:..:..::||:.|.       .|.|....|| ..||        :|.....|...:||...|.
Mouse   203 TSEKMKKRKMTSSFHG-------IRPPQLEQPE-KMPV--------LKAEASHYHSDLNNLLLCC 251

  Fly   501 EEMGEVLKSSTFSAGANDKLKWCLRV---NPK--GLDEESKDYLSLYLLLVSCNKSEVRAKFKFS 560
            :                     |:.|   :|:  |:.|..|        :|.|:.|.|     |.
Mouse   252 Q---------------------CVDVVFYHPEVTGVVEAHK--------IVLCSVSHV-----FM 282

  Fly   561 IL-NAK-----REETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPED-------KLTI 612
            :| |.|     ::.:....:|..:.            |.||.:|..|:...|.:       |..:
Mouse   283 LLFNVKSPADIQDSSIIRTTQDLFA------------INRDAVLPGASQEAPSNPPLPVIVKDAL 335

  Fly   613 FCEVSVVADSVNI---------------------SGQ-SNIVQ-----FKVP-------ECK--- 640
            ||  |.::|.:..                     ||. |:|::     .|.|       .||
Mouse   336 FC--SCLSDILRFIYSGAFQWEELEEDVRRKLKDSGDVSDIIEKVKCILKTPGKINCLRNCKTYQ 398

  Fly   641 -------LSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAI 698
                   .:..|....:....:||...:.|....||:|||.||.:|.||||.....|.|...:.:
Mouse   399 ARKPLWFYNTSLKFFLNKPMLADVVFEIQGATVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPV 463

  Fly   699 TDVDHEVLKEMLRFIYTGK---APNLEKMADDLLAAADKYALEKLKVMCEEALCVNL----SVET 756
            ..|..|.....|.::||..   |...:.|.  ||..|:.|.:.:|:.:||..:...|    |.|.
Mouse   464 YGVSKETFLSFLEYLYTDSCCPAGIFQAMC--LLICAEMYQVSRLQHICELFIITQLQSMPSREL 526

  Fly   757 AAETLILADL------HSADQLKAQTIDFINTH 783
            |:..|.:.||      |.:|.|....:.||.|:
Mouse   527 ASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATN 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	30/155 (19%)
		BTB_POZ_roadkill-like	637..757	CDD:349654	38/143 (27%)
		BACK_roadkill_like	752..825	CDD:350595	13/42 (31%)
Rhobtb3	NP_082769.1	Rho-like	1..175		7/36 (19%)
		P-loop containing Nucleoside Triphosphate Hydrolases	34..174	CDD:476819	7/35 (20%)
		BTB1_POZ_RHOBTB3	236..393	CDD:349666	36/204 (18%)
		BTB2_POZ_RHOBTB3	410..519	CDD:349669	32/110 (29%)
		Interaction with Rab9. /evidence=ECO:0000250	420..611		44/142 (31%)
		BACK_RHOBTB3	529..611	CDD:350607	9/31 (29%)