Protein Alignment rdx and KLHL25

DIOPT Version :10

• Sequence 1: NP_650326.3
• Gene: rdx / 41704
• FlyBaseID: FBgn0264493
• Length: 829
• Species: Drosophila melanogaster
• Sequence 2: XP_054234589.1
• Gene: KLHL25 / 64410
• HGNCID: 25732
• Length: 619
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 61/226 - (26%)
• Similarity: 95/226 - (42%)
• Gaps: 19/226 - (8%)

  Fly   611 TIFCEVSVVADSVNISGQSNIVQF---KVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQAHKAI 672
            |:...|.....|.:.:|..|:..|   ..|:|.|:. |..|..:..|:||||..|.|.|..|:|:
Human    30 TMSVSVHETRKSRSSTGSMNVTLFHKASHPDCVLAH-LNTLRKHCMFTDVTLWAGDRAFPCHRAV 93

  Fly   673 LAARSDVFAAMFEHEMEERKLNRVAITDVDH-EVLKEMLRFIYTGKAPNLEKMADDLLAAADKYA 736
            |||.|..|.|||.|.:.|.:.:.|...|..| |||:.:|.|.|:.:....|:.|:.||.|.|...
Human    94 LAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQ 158

  Fly   737 LEKLKVMCEEALCVNLSVETAAETLILADLHSADQL--------------KAQTIDFINTHATDV 787
            ...::....|.|..||........::|:|.|...:|              ..|:.||.:.....:
Human   159 FHDVRDAAAEFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFETVRQSEDFNSLSKDTL 223

  Fly   788 METSGWQNMITTHSHLIAEAFRALATQQIPP 818
            ::......:.|....::.||........:.|
Human   224 LDLISSDELETEDERVVFEAILQWVKHDLEP 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	2/9 (22%)
		BTB_POZ_roadkill-like	637..757	CDD:349654	44/120 (37%)
		BACK_roadkill_like	752..825	CDD:350595	12/81 (15%)
KLHL25	XP_054234589.1	BTB_POZ_KLHL25	54..181	CDD:349563	44/127 (35%)
		PHA03098	69..596	CDD:222983	51/186 (27%)
		BACK_KLHL25_ENC2	174..272	CDD:350589	12/81 (15%)
		KELCH repeat	360..404	CDD:276965
		KELCH repeat	408..461	CDD:276965
		KELCH repeat	464..510	CDD:276965
		KELCH repeat	512..554	CDD:276965