DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdx and spopla

DIOPT Version :9

Sequence 1:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	NP_001013465.1	Gene:	spopla / 541318	ZFINID:	ZDB-GENE-050320-3	Length:	392	Species:	Danio rerio

Alignment Length:	392	Identity:	300/392 - (76%)
Similarity:	338/392 - (86%)	Gaps:	20/392 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   458 VSRVPSPPLP-EVNT-PVAENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKL 520
            :|.||:||.| |::: ||||:|||||||||||||||||||||||||||||||||||||:|.|||:
Zfish     1 MSGVPTPPPPGEMSSGPVAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSGPNDKM 65

  Fly   521 KWCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKD 585
            ||||||||||||:|||||||||||||||.|||||||||||:||||||||||||||||||||||||
Zfish    66 KWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQRAYRFVQGKD 130

  Fly   586 WGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFD 650
            |||||||||||||||||||||:||||:|||||||.||||||||||:...|||||:||:|||||::
Zfish   131 WGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQSNMNMLKVPECQLSDDLGNLWE 195

  Fly   651 NEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYT 715
            ..:|:|.:|.|||:||:|||:||||||.||.|||||||||.|.|||.|:||:.||.|||:.||||
Zfish   196 CSRFTDCSLYVGGQEFKAHKSILAARSPVFNAMFEHEMEESKKNRVDISDVEPEVFKEMMGFIYT 260

  Fly   716 GKAPNLEKMADDLLAAADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFI 780
            |||||||||||.|||||||||||:||||||||||.:||||..|:||||||||||:|||||.||||
Zfish   261 GKAPNLEKMADSLLAAADKYALERLKVMCEEALCNSLSVENVADTLILADLHSAEQLKAQAIDFI 325

  Fly   781 N------------------THATDVMETSGWQNMITTHSHLIAEAFRALATQQIPPIGPPRKRVK 827
            |                  .||||:|||:||::||.:|.||:||||||||:.|.|..|.||||:|
Zfish   326 NRCSVLRQLGCKDGKNWNSNHATDIMETAGWKSMIQSHPHLVAEAFRALASAQCPHFGLPRKRLK 390

  Fly   828 MS 829
            .|
Zfish   391 QS 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	129/137 (94%)
		BTB	645..749	CDD:279045	78/103 (76%)
		BTB	656..752	CDD:197585	75/95 (79%)
		SPOP_C	752..814	CDD:269807	47/79 (59%)
spopla	NP_001013465.1	MATH	28..166	CDD:295307	129/137 (94%)
		BTB	190..294	CDD:279045	78/103 (76%)
		BTB	201..297	CDD:197585	75/95 (79%)
		SPOP_C	297..377	CDD:269807	47/79 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	192	1.000	Domainoid score	I3162
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D864323at2759
OrthoFinder	1	1.000	-	-		FOG0000398
OrthoInspector	1	1.000	-	-		otm25147
orthoMCL	1	0.900	-	-		OOG6_101509
Panther	1	1.100	-	-	LDO	PTHR24413
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2421
SonicParanoid	1	1.000	-	-		X131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.950