DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdx and Tdpoz2

DIOPT Version :9

Sequence 1:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	NP_001007223.2	Gene:	Tdpoz2 / 399673	MGIID:	3027902	Length:	360	Species:	Mus musculus

Alignment Length:	344	Identity:	184/344 - (53%)
Similarity:	246/344 - (71%)	Gaps:	2/344 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 AENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDY 538
            |:.|..||:.|.:|.|.|||:|||||...:...:||..||..||:::.|||||:|.|.|||||||
Mouse     7 AKIWGSTQISVKEFCYEWTISNFSFCMGGIRRKIKSPVFSLEANEEVAWCLRVHPNGFDEESKDY 71

  Fly   539 LSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANG 603
            ||:||:||:|.|.:|||||:|.|.|::.|:.:..:|.....|.:.::|||.|||.||.||...|.
Mouse    72 LSVYLVLVNCPKRQVRAKFEFWIKNSQGEKYQYTQSLNVPSFQRKQNWGFSKFILRDSLLSHRNW 136

  Fly   604 LLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQA 668
            |||:||||:.|:||:|...:|:.||:.|...|.|...|::|||.|::|..|:|.:|.|.|.||:|
Mouse   137 LLPKDKLTLCCKVSIVGAILNMPGQNMIPAIKDPRHMLTDDLGKLWENSLFTDCSLLVAGHEFRA 201

  Fly   669 HKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNL--EKMADDLLAA 731
            ||.||||||.||.||||.:||||..|...|.::|.:|.|||:.||||||||.|  ..||.|:|||
Mouse   202 HKVILAARSPVFRAMFEPQMEERLANCFEIQELDFQVFKEMMDFIYTGKAPTLHSHSMACDVLAA 266

  Fly   732 ADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNM 796
            ||||.||.|||:||::||.|:|||.||.|||:|||||.:|||.:.:.||..||::|.::|||::|
Mouse   267 ADKYGLEGLKVICEDSLCRNVSVENAAHTLIVADLHSTEQLKTRALHFIAVHASEVSKSSGWKSM 331

  Fly   797 ITTHSHLIAEAFRALATQQ 815
            :.:|.||:.|.||:||:.|
Mouse   332 VESHPHLVDERFRSLASAQ 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	72/137 (53%)
		BTB	645..749	CDD:279045	63/105 (60%)
		BTB	656..752	CDD:197585	60/97 (62%)
		SPOP_C	752..814	CDD:269807	33/61 (54%)
Tdpoz2	NP_001007223.2	MATH	16..153	CDD:295307	71/136 (52%)
		BTB	178..284	CDD:279045	63/105 (60%)
		BTB	189..286	CDD:197585	60/96 (63%)
		SPOP_C	287..349	CDD:269807	33/61 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D864323at2759
OrthoFinder	1	1.000	-	-		FOG0000398
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24413
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X131
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020