DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdx and RGD1566337

DIOPT Version :9

Sequence 1:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	XP_003749378.2	Gene:	RGD1566337 / 310589	RGDID:	1566337	Length:	364	Species:	Rattus norvegicus

Alignment Length:	357	Identity:	186/357 - (52%)
Similarity:	244/357 - (68%)	Gaps:	2/357 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 AENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDY 538
            |:::.||...|..|.|.|||:|||||.:.:.|.:.|..||..||::::||||::|.|.|||||||
  Rat     7 AKSYGYTHSSVQNFCYEWTISNFSFCMDGIRENIASPVFSFEANEEVEWCLRIHPNGFDEESKDY 71

  Fly   539 LSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANG 603
            ||:||.|:||..|.|.||.:|.|:||:.|:.:..:.....||:..:.||||.||.|||||...:.
  Rat    72 LSVYLWLLSCPDSPVLAKVQFWIINAQGEKHQISKMPNVLRFMPNQLWGFKNFILRDFLLSHRHW 136

  Fly   604 LLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQA 668
            |||||:||:.|:||:|....:....:.|...:.....||:|||.|::|..|:|.:|.|.|:||:|
  Rat   137 LLPEDQLTLCCKVSIVGPFFSRPEHNTIPAIRDQRQVLSDDLGELWENFIFTDCSLVVAGQEFRA 201

  Fly   669 HKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNL--EKMADDLLAA 731
            |||||||||.||.|||||||.|...||:.|.|:...|.|||:.||||||||:|  ..||..||||
  Rat   202 HKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLHVFKEMMGFIYTGKAPHLHSHSMATRLLAA 266

  Fly   732 ADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNM 796
            ||.|.|:.||||||:|||.|||||.|..||||||.||.:.||.:.:|||..||::|.||.||::|
  Rat   267 ADMYDLQDLKVMCEDALCRNLSVENAVSTLILADFHSTEHLKTKAMDFIILHASEVSETLGWKSM 331

  Fly   797 ITTHSHLIAEAFRALATQQIPPIGPPRKRVKM 828
            :.:|.||:.||||:||:.|.|.:.|..||.|:
  Rat   332 VESHPHLVEEAFRSLASIQCPFLEPSLKRRKI 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	70/137 (51%)
		BTB	645..749	CDD:279045	65/105 (62%)
		BTB	656..752	CDD:197585	62/97 (64%)
		SPOP_C	752..814	CDD:269807	35/61 (57%)
RGD1566337	XP_003749378.2	MATH	16..153	CDD:351761	69/136 (51%)
		BTB_POZ	165..292	CDD:365784	75/126 (60%)
		BACK	287..353	CDD:421692	36/65 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D864323at2759
OrthoFinder	1	1.000	-	-		FOG0000398
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24413
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X131
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020