DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdx and BTBD8

DIOPT Version :9

Sequence 1:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	NP_001363060.1	Gene:	BTBD8 / 284697	HGNCID:	21019	Length:	1792	Species:	Homo sapiens

Alignment Length:	158	Identity:	51/158 - (32%)
Similarity:	72/158 - (45%)	Gaps:	11/158 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   637 PECKLSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDV 701
            |..:|.|||..|:......|:.:.|.|:.|:||:|||:|||..||||......|.....|.:..:
Human   188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGI 252

  Fly   702 DHEVLKEMLRFIYTGKAPNLEKM-ADDLLAAADKYALEKLKVMCEEAL----C------VNLSVE 755
            .|..|..|:.|||.|.....:|. ...:|..||.|.||.||.:....|    |      |..::.
Human   253 SHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRTLT 317

  Fly   756 TAAETLILADLHSADQLKAQTIDFINTH 783
            :..|.||:|.....:.|.|..:.:|..|
Human   318 SILECLIIAHSVGVESLFADCMKWIVKH 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743
		BTB	645..749	CDD:279045	37/108 (34%)
		BTB	656..752	CDD:197585	37/106 (35%)
		SPOP_C	752..814	CDD:269807	8/32 (25%)
BTBD8	NP_001363060.1	BTB1_POZ_BTBD8	43..147	CDD:349594
		BTB2_POZ_BTBD8	189..309	CDD:349595	41/119 (34%)
		BACK_BTBD8	316..378	CDD:350565	8/30 (27%)
		BACK	396..>451	CDD:391941
		DUF4596	1749..1792	CDD:373786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910