Protein Alignment rdx and RHOBTB3

DIOPT Version :10

• Sequence 1: NP_650326.3
• Gene: rdx / 41704
• FlyBaseID: FBgn0264493
• Length: 829
• Species: Drosophila melanogaster
• Sequence 2: NP_055714.3
• Gene: RHOBTB3 / 22836
• HGNCID: 18757
• Length: 611
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 103/484 - (21%)
• Similarity: 159/484 - (32%)
• Gaps: 159/484 - (32%)

  Fly   397 NQQQPQQSPLCLVLLVKCPNSKE--------------------------FCNAAANFCDKRLPVN 435
            |::.|...|||......|.::.|                          |......|..:.|...
Human   138 NEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDFYIGKYFGGVLEYFMIQALNQK 202

  Fly   436 ECQASQTARVTSNLHASSSTMAVSRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCR 500
            ..:..:..:::::.|.       .|.|....|| ..||        :|.....|...:||..||.
Human   203 TSEKMKKRKMSNSFHG-------IRPPQLEQPE-KMPV--------LKAEASHYNSDLNNLLFCC 251

  Fly   501 EEMGEVLKSSTFSAGANDKLKWCLRV---NP--KGLDEESKDYLSLYLLLVSCNKSEVRAKFKFS 560
            :                     |:.|   ||  |.:.|..|        :|.|..|.|     |.
Human   252 Q---------------------CVDVVFYNPNLKKVVEAHK--------IVLCAVSHV-----FM 282

  Fly   561 ILNAKREETKAMESQ--RAYR--FVQGKDWGFKKFIRRDFLLDEANG-----LLPEDKLTIFCEV 616
            :|...:..|...:|.  |..:  |...:|..|..      ...|::|     ::.:|.|  ||
Human   283 LLFNVKSPTDIQDSSIIRTTQDLFAINRDTAFPG------ASHESSGNPPLRVIVKDAL--FC-- 337

  Fly   617 SVVADSVNI---------------------SGQ-SNIVQ-----FKVP-------ECK------- 640
            |.::|.:..                     ||. ||:::     .|.|       .||
Human   338 SCLSDILRFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKP 402

  Fly   641 ---LSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVD 702
               .:..|....:....:||...:.|....||:|||.||.:|.||||.....|.|...:.:..|.
Human   403 LWFYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVS 467

  Fly   703 HEVLKEMLRFIYTGK---APNLEKMADDLLAAADKYALEKLKVMCEEALCVNL----SVETAAET 760
            .|.....|.::||..   |...:.|.  ||..|:.|.:.:|:.:||..:...|    |.|.|:..
Human   468 KETFLSFLEYLYTDSCCPAGIFQAMC--LLICAEMYQVSRLQHICELFIITQLQSMPSRELASMN 530

  Fly   761 LILADL------HSADQLKAQTIDFINTH 783
            |.:.||      |.:|.|....:.||.|:
Human   531 LDIVDLLKKAKFHHSDCLSTWLLHFIATN 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	32/151 (21%)
		BTB_POZ_roadkill-like	637..757	CDD:349654	38/143 (27%)
		BACK_roadkill_like	752..825	CDD:350595	13/42 (31%)
RHOBTB3	NP_055714.3	Rho-like	1..175		7/36 (19%)
		P-loop containing Nucleoside Triphosphate Hydrolases	34..174	CDD:476819	7/35 (20%)
		BTB1_POZ_RHOBTB3	236..393	CDD:349666	38/200 (19%)
		BTB2_POZ_RHOBTB3	410..519	CDD:349669	32/110 (29%)
		Interaction with Rab9	420..611		44/142 (31%)
		BACK_RHOBTB3	529..611	CDD:350607	9/31 (29%)