Protein Alignment rdx and Spop

DIOPT Version :10

• Sequence 1: NP_650326.3
• Gene: rdx / 41704
• FlyBaseID: FBgn0264493
• Length: 829
• Species: Drosophila melanogaster
• Sequence 2: NP_079563.2
• Gene: Spop / 20747
• MGIID: 1343085
• Length: 374
• Species: Mus musculus
• Alignment Length: 374
• Identity: 298/374 - (79%)
• Similarity: 338/374 - (90%)
• Gaps: 2/374 - (0%)

  Fly   458 VSRVPSPPLP-EVNT-PVAENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKL 520
            :|||||||.| |::: ||||:|||||:||||||||||||||||||||||||:||||||:||||||
Mouse     1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKL 65

  Fly   521 KWCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKD 585
            ||||||||||||||||||||||||||||.||||||||||||||||.|||||||||||||||||||
Mouse    66 KWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKD 130

  Fly   586 WGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFD 650
            |||||||||||||||||||||:||||:|||||||.||||||||:.:...|||||:|:::||.|::
Mouse   131 WGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWE 195

  Fly   651 NEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYT 715
            |.:|:|..|.|.|:|||||||||||||.||:|||||||||.|.|||.|.||:.||.|||:.||||
Mouse   196 NSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYT 260

  Fly   716 GKAPNLEKMADDLLAAADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFI 780
            ||||||:||||||||||||||||:||||||:|||.|||||.|||.|||||||||||||.|.:|||
Mouse   261 GKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFI 325

  Fly   781 NTHATDVMETSGWQNMITTHSHLIAEAFRALATQQIPPIGPPRKRVKMS 829
            |.||:||:|||||::|:.:|.||:|||:|:||:.|.|.:||||||:|.|
Mouse   326 NYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	131/137 (96%)
		BTB_POZ_roadkill-like	637..757	CDD:349654	89/119 (75%)
		BACK_roadkill_like	752..825	CDD:350595	50/72 (69%)
Spop	NP_079563.2	MATH_SPOP	28..166	CDD:239743	131/137 (96%)
		Required for nuclear localization. /evidence=ECO:0000250	71..191		104/119 (87%)
		Important for binding substrate proteins. /evidence=ECO:0000250	123..133		9/9 (100%)
		BTB_POZ_SPOP-like	182..301	CDD:349588	88/118 (75%)
		Important for homodimerization. /evidence=ECO:0000250	186..217		16/30 (53%)
		BACK_SPOP	297..367	CDD:350593	47/69 (68%)
		Important for homodimerization. /evidence=ECO:0000250	297..355		41/57 (72%)