DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdx and bath-41

DIOPT Version :9

Sequence 1:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	NP_498473.1	Gene:	bath-41 / 175946	WormBaseID:	WBGene00018137	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	384	Identity:	89/384 - (23%)
Similarity:	158/384 - (41%)	Gaps:	41/384 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   459 SRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCRE--EMGEVLKSSTFSAGANDKLK 521
            ||.||....:..:|...:.|.|.:....|:..|::..|:...|  ...|.:.:..|..|   ..:
Worm    18 SRSPSGKSEKRKSPSIVSGCRTVMNERSFTNYWSVERFTVQLELHNPAEFMLAPKFGDG---DYE 79

  Fly   522 WCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREET----KAMESQRAYRFVQ 582
            :.:::.|.|.|||:..||||:||:..|....:|.:..|::..|....:    |.:.:......|.
Worm    80 FVMKLFPNGKDEETAGYLSLFLLINKCPNPRLRFRVSFTVETADGPRSCHLNKNLVTINRSGIVT 144

  Fly   583 GKDWGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVAD----------------SVNISGQS-- 629
            .     .||...|.|....|..:|.|.|||.||:::..:                |.:.:.:|
Worm   145 A-----SKFFSLDILRSAMNVYIPNDILTIGCELTIFGECTTQISSLFKPYQRTHSASSTSRSLS 204

  Fly   630 --NIVQFKVPECKLSEDLGNLFDNEKFSD-VTLSVGGREFQAHKAILAARSDVFAAMF-EHEMEE 690
              |....|:.|....:.........:||| :.::..||||..|..||||||:.|..:. .|..:|
Worm   205 SPNTKCLKIDESSAHDAFTEFLSTGEFSDFIIVASCGREFPTHMCILAARSEYFKVLLRNHSTKE 269

  Fly   691 RKLNRVAITDVDHEVLKEMLRFIY---TGKAPNLE--KMADDLLAAADKYALEKLKVMCEEALCV 750
            ....|:...|:....|..:||.:|   .|:...||  ::.:||::|.|:..:..|:......:..
Worm   270 FMSKRLQFDDISARTLDVLLRHMYASAAGRVVKLEEDQLTEDLISAMDRLMINSLRDEVARLIGS 334

  Fly   751 NLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNMITTHSHLIAEAFR 809
            .::|:.....:.:|.....|......:||.:.|..:.|:.:.|..:.:....|..:..|
Worm   335 KVTVDNVLTRISMAAELRLDDTYDVLLDFFSNHKHECMKLTAWDELESAKPPLAIKILR 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	36/143 (25%)
		BTB	645..749	CDD:279045	31/110 (28%)
		BTB	656..752	CDD:197585	29/102 (28%)
		SPOP_C	752..814	CDD:269807	10/58 (17%)
bath-41	NP_498473.1	MATH	43..178	CDD:295307	36/142 (25%)
		BTB	222..332	CDD:279045	31/109 (28%)
		BTB	233..332	CDD:197585	29/98 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1987
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D864323at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24413
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920