Protein Alignment Orc2 and ORC2

DIOPT Version :10

• Sequence 1: NP_731873.1
• Gene: Orc2 / 41703
• FlyBaseID: FBgn0015270
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_181292.1
• Gene: ORC2 / 818332
• AraportID: AT2G37560
• Length: 363
• Species: Arabidopsis thaliana
• Alignment Length: 650
• Identity: 162/650 - (24%)
• Similarity: 275/650 - (42%)
• Gaps: 106/650 - (16%)

  Fly    18 MSIENLTNSEEESEDLNTAMVGNAVESQPKVTSR-------RSTRRPSPTKKYQAYQKESNGKGQ 75
            ::| |. ...| ||. |....|.:.. . .:| |       .|.....|. . .|... ..|..:
plant   253 ITIONCOMPLEXSECONDLARGESTSUBUNITORCCONTAINSINTERPRODOMAINSORIGINR 317

  Fly    76 E--ERIVVNYVEMSDERSSDAEDQEEEESIEESENAARPA-----AKDL---HLIQSEYNVAGTS 130
            |  ..|.: .. |..| | :          ..:.|..||.     |.:|   |:..:   .. |.
plant   318 ECOGNITIONCOMPLEXSUB---------UNITINTERPROIPRHASBLASTHITST--OPROTE 371

  Fly   131 MFGFNTPKKRDAMALAALNATPCTPKTPKTPRLGVKTPDTKRKKSMDQPKT----PAHVRTRVKK 191
            :...|:|:        .:.:..|..:...|.|:.::|.: .. ..:....|     :.. |..::
plant   372 INSINSPE--------CIESARCHAEBACTERIAMETAZOAFUNGIPLANTSVIRUSESOTHERE 428

  Fly   192 QIAKIVADSDEDFSG-------DESDFRPSDEESSSSSSSSDAGNSSDNDAADDEPKTPSRARRA 249
             .|:. .:|.  ...       ::.: |...... .:::..: ....:|:..|:      |...|
plant   429 UKARYOTESSOURCENCBIBLINKDBXREFARAPORTATGDBXREFGENEIDDB-----XREFTA 488

  Fly   250 IVVPVLPKTPSAARLRQSARAKKSNEFVPESD-GYFHSHASSKIL--TSDHTLDRLKNPRLAADR 311
            |                .|...:..|.:.|.: |:..::..:|.|  .|..:..:|.:..:..::
plant   489 I----------------RATGMEDIENIEEDEYGFSRNYFLAKELGGASKRSAHKLSDIHIVDEQ 537

  Fly   312 VFSLLSEIKTSA-----EHEGSINAIMEEYRSYFPKWMCILNEGFNILLYGLGSKHQLLQSFHRE 371
                  |::.:|     :|...|:.:|.:|::.:.||:..|..||.:|:||.|||..|::.|...
plant   538 ------ELRETASTIEMKHSKEISELMSDYKTMYSKWVFELRCGFGLLMYGFGSKKALVEDFASA 596

  Fly   372 VLHKQTVLVVNGFFPSLTIKDM---LDSITSDIL------DAGISPAN---PHEAVDMIEEEFAL 424
            .|...:|:|:||:.||:.:|.:   |..:.|::|      ...:|...   |..::|.| ..|..
plant   597 SLTDYSVVVINGYLPSVNLKQVLLALAELLSELLKCKRKSSGSLSKGQETFPSRSMDDI-LSFLH 660

  Fly   425 IPET-----HLFLIVHNLDGAMLRNVKAQAILSRLARIPNIHLLASIDHINTPLLWDQGKLC--S 482
            .|::     .:.::|||:||..||:.::|..|:||:...:|.|:|||||:|.|||||: |:.  .
plant   661 GPQSGDKDCFICVVVHNIDGPALRDPESQQTLARLSSCSHIRLVASIDHVNAPLLWDK-KMVHKQ 724

  Fly   483 FNFSWWDCTTMLPYTNETAFENSLLVQNSGELALSSMRSVFSSLTTNSRGIYMLIVKYQLKNKGN 547
            ||:.|....|..||..|..|...:|.|.|......:...|..|||.|.:.::.::.:|||.:...
plant   725 FNWLWHHVPTFAPYNVEGVFFPLVLAQGSTAQTAKTAAIVLQSLTPNGQNVFKILAEYQLSHPDE 789

  Fly   548 ATYQGMPFRDLYSSCREAFLVSSDLALRAQLTEFLDHKLVKSKRSVDGSEQLTIPIDGALLQQFL 612
               .|||..||||:.||.|.|||.:.|.:.||||.||:|||:||:.||.|.|.||:....::|.|
plant   790 ---DGMPTDDLYSASRERFFVSSQVTLNSHLTEFKDHELVKTKRNSDGQECLNIPLTSDAIRQLL 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc2	NP_731873.1	PTZ00449	<136..310	CDD:185628	23/187 (12%)
		ORC2	296..604	CDD:461163	112/331 (34%)
ORC2	NP_181292.1	ORC2	33..353	CDD:461163	21/108 (19%)