Protein Alignment Kots and tdrd15

DIOPT Version :10

• Sequence 1: NP_650324.1
• Gene: Kots / 41702
• FlyBaseID: FBgn0038191
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_001182210.1
• Gene: tdrd15 / 799498
• ZFINID: ZDB-GENE-041014-303
• Length: 1883
• Species: Danio rerio
• Alignment Length: 918
• Identity: 177/918 - (19%)
• Similarity: 297/918 - (32%)
• Gaps: 323/918 - (35%)

  Fly    74 KTRTKSPIPCVEPTVA-----VPNKPDLSENWRKHLLPSGMEFFKCRVTFMENDGPIWVVHVANV 133
            |..:|.|.|||...|.     :..:|   ||...|.  .|.....|.:.:             |:
Zfish     5 KEESKLPAPCVLWPVELKLTHIDCRP---ENKLVHF--QGQYMTICELDY-------------NI 51

  Fly   134 EAIERMTVNMQRCMQNKKMIRMEGVREDTLVAISVGDKVHRGHVLTVCQKKQEANVRMIDHGQIV 198
                 :.|.:|..:::|..:::..|   .||..|...:.:||.|..:  :|.:.::.::|||
Zfish    52 -----LQVEIQNAVKSKVSVQVGDV---CLVEDSGSGRWYRGRVQNI--EKDKFHIFLLDHG--- 103

  Fly   199 ATPFRDIYTIVPKMAESKAFAFRVQLPTNTGVQDIKNLTLRMLGTKTSDGAYHVHLKPKMIIPLS 263
                 |:..:.|....|              :.|    ||.||..|...|.:      ..|:|:.
Zfish   104 -----DMMIVGPNCLSS--------------ISD----TLLMLPPKIVCGFF------ANILPIQ 139

  Fly   264 LPLEMLQLNPEVKVIRVFKANPKHNEPQLALLQINVMGHVNADLNNRIAEKPRQPFTLPFPEQKS 328
            ...:.|.                 |....:|....:.|:::|.|       |.....|..||..|
Zfish   140 SQWDSLT-----------------NSYFSSLKGSRIKGYIHARL-------PYHILILEVPEINS 180

  Fly   329 IFFAATRTKNGYRRAFLLDHIMKPRPTYLVYEM--DEGRVSIATDLSRIPSELLGLPSRVFAAQL 391
            ........::.....||           |:.||  ||          .||             |.
Zfish   181 DMIKKRLGRHVDTSTFL-----------LLVEMLIDE----------PIP-------------QS 211

  Fly   392 EDSVPEEL-ETQ-GAELTVKFKLDNKPPKEKLRAANAALNSKGEQICMARLITFLGQISYLGHKY 454
            .:|||:.| |.| |.|..:|        ...|......|:..|.::.:.:.:
Zfish   212 NESVPDLLIEKQIGQEYCLK--------SSSLLGFEEILSLNGPKLKVGQEV------------- 255

  Fly   455 WREPIVHDSI---VFISHLVSFKEVYISTPDAKQYAEIFKRLEYKCAT----ITKSSDVSVGSIV 512
              |.:|..::   :|...|.|.         .|...|:..:|...|.:    :|...|.::|.:.
Zfish   256 --EVVVAAAVNPGLFYCRLSSM---------GKDLQEMSDKLALACESGSGCLTNDLDENLGLLC 309

  Fly   513 LVVSKQMGHFRG--EILSKDSGLFEVMNVDTGATQKVELAEI-RSSCRFLENLPVCLMRVQLQNV 574
            .|..|.....||  |.|..:|.: :|:.||:|..:.|::..| :....||..
Zfish   310 AVKGKDEKWHRGFVECLPLNSQV-KVVFVDSGYCESVKVENILQLPSEFLSR------------- 360

  Fly   575 CNIPDAAVPVNNAAIQMLHKLCAQKELLKLNMVDATTSTV---DLLFSSGDSRSLTTQMLPLIFT 636
               |..|.|   .::..|.|   |.|.:|...|||..:.:   .|.....|.|.  .|.|.|:..
Zfish   361 ---PIMAFP---CSLSCLEK---QDEDIKNQQVDALKTGLLGKVLEIEIDDFRK--DQNLYLVTM 414

  Fly   637 PVQEK-----AEVAPPKAASTPSQ-------LPVVTHKQQKVSPQSLLLLDLPPLPPSPPESPFP 689
            .:.:|     |.|.|.::.:..|.       |..|:..:.||:..|    |..|....|.:|.|.
Zfish   415 NIAQKHSEKQAGVKPHESDNLRSNSNFPYDVLSNVSAGETKVAQTS----DSNPNRAIPDDSFFE 475

  Fly   690 ADVTSTKSASHV-LPIKRF--LFDALPKNLAPLGDKVNLILMNADGLPQTGYITAAYFKDEKAAK 751
            ..|...:|..|. :..|..  .|:.:.|.:|....|:.|
Zfish   476 GYVVHVQSPKHFWIRTKEHNPNFENMTKEMADYFSKLQL-------------------------- 514

  Fly   752 EFEKILSLTSSQGACDHNVVPGYVPNVGELCLAIYSEDKNWYRGVCQEVKDNMVKILFCDFGNTE 816
             .|::.          .::||      |.||.|:|..|..:||.:..:..|...::.|.||||||
Zfish   515 -HEEVF----------EDLVP------GALCCAMYENDMQYYRALVVDTLDKGAEVFFIDFGNTE 562

  Fly   817 YV----------------------AVRHVKP---------------ISQDLLIAVNVT-----KC 839
            .|                      |:.||.|               ::.|..:.::|.     |.
Zfish   563 KVPGILIKKLPKKFAIHPEFAMECALAHVAPHEDIWTTTASNYFREVTSDKTLMIHVVHRKNRKY 627

  Fly   840 YINGFDKSKNFAALEQFLVR----------------KIRFLCGV------KKGPEPDTRLITIPD 882
            .::.|::.....::...:..                :|...|..      ||..:.|.|::|...
Zfish   628 VVDLFERDAENCSIATIMTTAKMALDWRYNPALASVEIERPCKYKGNALSKKKNKKDLRVVTFHK 692

  Fly   883 METILNTP 890
            :.:.:::|
Zfish   693 VTSSMSSP 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kots	NP_650324.1	zf-MYND	9..44	CDD:460312
		TUDOR	110..225	CDD:425754	19/114 (17%)
		TUDOR	465..573	CDD:425754	25/114 (22%)
		TUDOR	743..843	CDD:425754	27/141 (19%)
tdrd15	NP_001182210.1	Tudor_TDRD15_rpt1	20..166	CDD:410507	38/222 (17%)
		Tudor_TDRD15_rpt2	251..371	CDD:410508	30/163 (18%)
		Tudor_SF	471..608	CDD:470623	35/179 (20%)
		Tudor_SF	733..855	CDD:470623
		Tudor_TDRD15_rpt5	940..1065	CDD:410511
		Tudor_TDRD15_rpt6	1233..1341	CDD:410512
		Tudor_SF	1613..1745	CDD:470623