Protein Alignment Kots and vret

DIOPT Version :10

• Sequence 1: NP_650324.1
• Gene: Kots / 41702
• FlyBaseID: FBgn0038191
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: NP_651092.1
• Gene: vret / 42695
• FlyBaseID: FBgn0263143
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 148/679 - (21%)
• Similarity: 240/679 - (35%)
• Gaps: 139/679 - (20%)

  Fly   206 YTIVPKMAESKAFAFRVQLPTNTGVQDIKNLTLRMLGTKTSDGAYHVHLKPKMIIPLSLPLEMLQ 270
            |.:|||   |..:.....|....|...||.:..|.|..     .|.|:.  :.|..|....:.:|
  Fly    60 YLVVPK---SSPYVTEKMLINFFGRALIKEMEFRRLSR-----VYFVYF--ENIASLETAQQRVQ 114

  Fly   271 LNPEVKVIRVFKANPKH-----NEPQLALLQINVMG-HVNADLNNRIAEKPRQPFTLPFPEQKSI 329
            ..|  .:|:.....|:.     ::|..:...:...| .::|.....:......|.:.........
  Fly   115 RYP--NLIKCITGRPQKEREITSDPVTSTEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEF 177

  Fly   330 FFAATRTKNGYRRAFLL---DHIMKPRPTYLVYEMDEGRVSIATDLSRIPSELL------GLPSR 385
            |.....||:.|:|..||   |.|.:.......:.::...:....|.:|||..:|      .:|..
  Fly   178 FRPPLVTKDDYKRGSLLATNDPIQRYLNVKYEFALERHDIYKLKDETRIPQVVLHFRSGRTIPLS 242

  Fly   386 VFAAQLEDSVPEELETQGAELTV------KF-KLDNKPPKEKLRAANAALNSKGEQICMARLITF 443
            ..|...||.....||...::..|      .| ||...|.......|:.|...|  |.|....|..
  Fly   243 TVAVTEEDKTKSLLEDGVSKCVVCQNWTDTFCKLCKMPFCNASCFADVAEQHK--QACGKGEILN 305

  Fly   444 LGQISYLGHKYWREPI-VHDSIVFISHLVSFKEVYISTPDAK---QYAEIFKRLEY--KCATITK 502
            |.:  .:|.||.:..: ...|.|.|:.......||:.:.|.:   .|..:...:..  |.|:..:
  Fly   306 LDE--KVGRKYPKPGLPPSGSKVRITAFEQTNVVYVRSADIQIDIAYYTVLTEVMMLGKDASKLQ 368

  Fly   503 SSDVSVGSIVLVVSKQMGHF-RGEILSKDSGLFE--VMNVDTGATQKVELAEIRSSCRFLENLPV 564
            |:.| .|.|||.  |..||. |..:|:.|: :.|  |:.:|.|:.:..:|..:.....:|..|..
  Fly   369 STPV-CGQIVLY--KFEGHMSRAMVLNVDN-IKEIYVVFIDFGSVEVTQLERLYECSSYLAGLTC 429

  Fly   565 CLMRVQLQNVCNIPDAAVPVNNAAIQMLHKLCAQKELLKLNMVDATTSTV-DLLFSSGDSRSLTT 628
            ..:.|:|:.|   |...|..|                ::..|.:...|.| ::.:|   ||...|
  Fly   430 YPVAVKLRGV---PRRFVGPN----------------IREVMYELDQSLVFNIKYS---SREYDT 472

  Fly   629 QMLPLIFTPVQEKAEVAPPKAASTPSQLPVVTHKQQKVSPQSLLLLDLPPLPPSPPESPFPADVT 693
                                  |...|:.|:|......|...|....|.|:.||..:..:..
  Fly   473 ----------------------SKGMQVVVMTEIDINRSLNRLFKTILTPVEPSVSDLGYKE--- 512

  Fly   694 STKSASHVLPIKRFLFDALPKNLAPLGDKVNLILMNADGLPQTGY-----ITAAY--FKDEKAAK 751
                            |.||......|..:|:::|: :...|.|:     |..||  .|.::..:
  Fly   513 ----------------DCLPYIPLHCGKNINVVVMD-NTFIQCGFIYCTSIDLAYEVTKMQRDIQ 560

  Fly   752 EF-EKILSLTSSQGACDHNVVPGYVPNVGELCLAIYSEDKNWYRGVCQE-VKDNMVKILFCDFGN 814
            |: |||....:            |.|.:.|||:|.|  :..|.||:..| |.|....|||.|:||
  Fly   561 EYGEKIAKCAT------------YAPPINELCIAKY--EGKWRRGLSVELVGDGYPSILFIDYGN 611

  Fly   815 TEYVAVRHVKPISQDLLIAVNVTKCYING 843
            .....|..::|.....:..:..|:..:.|
  Fly   612 IVPTHVTDIRPYPPQFIFPIMTTQLDLIG 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kots	NP_650324.1	zf-MYND	9..44	CDD:460312
		TUDOR	110..225	CDD:425754	5/18 (28%)
		TUDOR	465..573	CDD:425754	29/115 (25%)
		TUDOR	743..843	CDD:425754	28/103 (27%)
vret	NP_651092.1	TUDOR	322..438	CDD:425754	30/119 (25%)
		Tudor_vreteno-like_rpt1	371..424	CDD:410515	16/56 (29%)
		TUDOR	524..640	CDD:425754	34/130 (26%)
		Tudor_vreteno-like_rpt2	576..631	CDD:410516	19/56 (34%)