Protein Alignment Kots and tdrd7a

DIOPT Version :10

• Sequence 1: NP_650324.1
• Gene: Kots / 41702
• FlyBaseID: FBgn0038191
• Length: 892
• Species: Drosophila melanogaster
• Sequence 2: XP_073788061.1
• Gene: tdrd7a / 406379
• ZFINID: ZDB-GENE-040426-2103
• Length: 1109
• Species: Danio rerio
• Alignment Length: 635
• Identity: 127/635 - (20%)
• Similarity: 212/635 - (33%)
• Gaps: 209/635 - (32%)

  Fly   341 RRAFLLDHIMKPR-----PTYLVYEMDEGRVSI-----------ATDLSRIPSELLGLPSRVFAA 389
            |.:.|..|.:|||     |:.:.:   .||.|:           :|||   ||      ||..|.
Zfish   139 RTSHLFSHNVKPRLSLRQPSSMTH---PGRGSVTSFYSTQRKLYSTDL---PS------SRAPAW 191

  Fly   390 QL--EDSVPEELETQGAELTVKFKLDNKPPKEKLRAANAALNSKGEQICMARLITFLGQISYLGH 452
            |:  :..|||:...    :..|...:.|.|.:|.....|    :.:.:..|.:....|:|..|..
Zfish   192 QMNRKSPVPEKTSV----VPSKINTNIKTPLKKTSGTPA----QQKPVNRADVELVQGRIKQLLQ 248

  Fly   453 KY----W--REPIVHDSIVFISHLVSFKEV----YISTPDAKQYAEIFKRLEYK-CATITKSSDV 506
            ||    |  :.|.::.| :|...|...:||    :|.|.:......|..||.|. ...:.|:|.|
Zfish   249 KYSSGVWLSKIPQLYKS-MFQEELHIIQEVEKWTHICTVEKPGSNNIVDRLVYPVLEPVPKASPV 312

  Fly   507 SVGSIVLVVSKQMGHFRGEILSKDSGLFEVMNVDTGATQKVELAEIRSSCRFLENLPVCLMRVQL 571
            .|.|    ..||         |.::.|.:...:    |||        :.|....|.:
Zfish   313 PVKS----PCKQ---------SPNTALLKQPTL----TQK--------TTRTFRTLAI------- 345

  Fly   572 QNVCNIPDAAVPVNNAAIQMLHKLCAQKELLKLNMVDATTSTVDLLFSSGDSRSLTTQMLPLIFT 636
                |||.:                ..|....|:.....::.:|...|.               |
Zfish   346 ----NIPQS----------------TPKPQTPLSPTSPNSTMIDFTLSE---------------T 375

  Fly   637 P-VQEKAEVAPPKAASTPSQLPVVTHKQQKVS---------------------------PQSLL- 672
            | .|..:.:.||  ::.|:..|:.|..:||:.                           ||.:|
Zfish   376 PKTQSLSPITPP--STPPAHQPLTTELKQKLRQLLNKYSQGLWAHGLPQLFQEAFGCAFPQYVLE 438

  Fly   673 -----------------------LLDLPPLPPSPPESPFPADVTSTKSASHVLPIKRFLFDALPK 714
                                   |..||....:.|.|..|..|....|..||.|:
Zfish   439 DLSLLADTCMVEYPMPDNRKRAILYTLPCQVQTQPRSRPPPLVLPCTSNPHVPPL---------- 493

  Fly   715 NLAPLGD--KVNLILMNADGLPQTGYITAAYFKDEKAAKEFEKILSLTSSQGACDHNVVPGYVPN 777
             :.|..|  .|.:|.:|:.......:....|.|..:..:|..:........|.|..:      |.
Zfish   494 -IIPTADFHSVFVIEINSTNNVVVRFAGEGYSKSLEVMEEEMQNFYNNIGAGLCLLS------PK 551

  Fly   778 VGELCLAIYSEDKNWYRGVCQEVKDNMVKILFCDFGNTEYVAVRHVKPI-SQDLLIAVNVTKCYI 841
            :|:| :|:.|.|....|....::.::.||:.|.|.|..:.|:.:.:..: .|.:.:....|.|.:
Zfish   552 IGQL-VAVASSDGAMLRAQVHQLSEDKVKVYFLDHGFFDLVSRKTIFQLRDQFMTLPFQATTCQL 615

  Fly   842 NGFD---------KSKNFAALEQFLVRKIRFLCGVKKGPEPDTRLITIPD 882
            .|.:         |:....|:.:.|:.:|     |::   .||.|:.:.|
Zfish   616 AGLEPFSTDPVVLKTLQSLAVGRSLLAEI-----VER---EDTPLVVLYD 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kots	NP_650324.1	zf-MYND	9..44	CDD:460312
		TUDOR	110..225	CDD:425754
		TUDOR	465..573	CDD:425754	24/112 (21%)
		TUDOR	743..843	CDD:425754	21/100 (21%)
tdrd7a	XP_073788061.1	None