DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9925 and INHBB

DIOPT Version :9

Sequence 1:	NP_650324.1	Gene:	CG9925 / 41702	FlyBaseID:	FBgn0038191	Length:	892	Species:	Drosophila melanogaster
Sequence 2:	NP_002184.2	Gene:	INHBB / 3625	HGNCID:	6067	Length:	407	Species:	Homo sapiens

Alignment Length:	108	Identity:	24/108 - (22%)
Similarity:	36/108 - (33%)	Gaps:	38/108 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   647 PKAASTPSQLPVVTHKQQKVSPQSLLLLDLPPLPPSPPESPFPADVTSTKSASHVLP-------- 703
            |:|..:|:..|         :|.:      || ||.||.||..:..|.|.......|
Human    24 PEAWGSPTPPP---------TPAA------PP-PPPPPGSPGGSQDTCTSCGGFRRPEELGRVDG 72

  Fly   704 -----IKRFLFDALPKNLAPLGDKVNLILMNADGLPQTGYITA 741
                 :||.:...|.....|     |:    ...:|:...:||
Human    73 DFLEAVKRHILSRLQMRGRP-----NI----THAVPKAAMVTA 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9925	NP_650324.1	zf-MYND	9..44	CDD:280009
		TUDOR	109..225	CDD:278965
		TUDOR	457..573	CDD:278965
		TUDOR	718..843	CDD:278965	5/24 (21%)
		TUDOR	779..825	CDD:119391
INHBB	NP_002184.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..62		14/51 (27%)
		TGFb_propeptide	57..278	CDD:279078	9/59 (15%)
		TGFB	303..406	CDD:214556
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1558
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950