DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9926 and HDGFL2

DIOPT Version :10

Sequence 1:NP_650323.2 Gene:CG9926 / 41700 FlyBaseID:FBgn0038190 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_001335098.1 Gene:HDGFL2 / 84717 HGNCID:14680 Length:695 Species:Homo sapiens


Alignment Length:228 Identity:44/228 - (19%)
Similarity:75/228 - (32%) Gaps:67/228 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 MPNFTIGDFVFAKLRRYR------PWPG-----------RILNRIGA--------------TAYS 41
            ||.::.|........|.|      |||.           |...|.|:              ..|.
Human     1 MPGWSSGGLNLGCFWRERDAGPGGPWPSPGARDSDKVALRRPKREGSWIDDIADGAVKPPPNKYP 65

  Fly    42 VYFYGSCNYAKVARKEVVDYEKNLHRLGVVQQKGHVCNPSFRASMLQAR-EAFDNPDKDYGYYQQ 105
            ::|:|:...|.:..|::..|:|...:.|         .|:.|....:.. |..:||...|.....
Human    66 IFFFGTHETAFLGPKDLFPYDKCKDKYG---------KPNKRKGFNEGLWEIQNNPHASYSAPPP 121

  Fly   106 LAVNNGDCINAEDLGLEYLVTEDLGNLLDEQAATEQVVAEKDVNEQVAVEQNVELNSLGQIFSNQ 170
            ::.::.:...|....         |:..||......|:|...|....|.::             .
Human   122 VSSSDSEAPEANPAD---------GSDADEDDEDRGVMAVTAVTATAASDR-------------M 164

  Fly   171 EHEKDSEDSASNCQLEEKDQSNSEVVKEQVSER 203
            |.:.||:.|:.|..|:.|    :..:|..||:|
Human   165 ESDSDSDKSSDNSGLKRK----TPALKMSVSKR 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9926NP_650323.2 PWWP 14..94 CDD:459964 20/111 (18%)
HDGFL2NP_001335098.1 PWWP <49..112 CDD:470613 11/71 (15%)
PTZ00121 <232..651 CDD:173412
LEDGF 496..593 CDD:463284
Blue background indicates that the domain is not in the aligned region.

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