DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9926 and PSIP1

DIOPT Version :10

Sequence 1:NP_650323.2 Gene:CG9926 / 41700 FlyBaseID:FBgn0038190 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_150091.2 Gene:PSIP1 / 11168 HGNCID:9527 Length:530 Species:Homo sapiens


Alignment Length:200 Identity:41/200 - (20%)
Similarity:71/200 - (35%) Gaps:80/200 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 NFTIGDFVFAKLRRYRPWPGRI-----------LNRIGATAYSVYFYGSCNYAKVARKEVVDYEK 63
            :|..||.:|||::.|..||.|:           .|::     .::|:|:...|.:..|::..|.:
Human     4 DFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKL-----PIFFFGTHETAFLGPKDIFPYSE 63

  Fly    64 NLHRLGVVQQKGHVCNPSFRASMLQAREAFDNPDKDYGYYQQL-AVNNGDCINAEDLGLEYLVTE 127
            |                         :|.:..|:|..|:.:.| .::|...:             
Human    64 N-------------------------KEKYGKPNKRKGFNEGLWEIDNNPKV------------- 90

  Fly   128 DLGNLLDEQAATEQVVAEKDVNEQVAVEQNVELNSLGQIFSNQEHEKDSEDSASNCQLEEKDQSN 192
               ....:||||:|..|..||                     :..||::..|..:...||| .||
Human    91 ---KFSSQQAATKQSNASSDV---------------------EVEEKETSVSKEDTDHEEK-ASN 130

  Fly   193 SEVVK 197
            .:|.|
Human   131 EDVTK 135

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9926NP_650323.2 PWWP 14..94 CDD:459964 17/90 (19%)
PSIP1NP_150091.2 PWWP_PSIP 5..92 CDD:438979 23/132 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..349 17/85 (20%)
PTZ00121 <89..525 CDD:173412 17/84 (20%)
Nuclear localization signal. /evidence=ECO:0000269|PubMed:15797927 146..156
Integrase-binding domain (IBD). /evidence=ECO:0000269|PubMed:15895093 340..417
LEDGF 349..450 CDD:463284
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 446..530
Blue background indicates that the domain is not in the aligned region.

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