DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and PRMT3

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_187835.2	Gene:	PRMT3 / 820407	AraportID:	AT3G12270	Length:	601	Species:	Arabidopsis thaliana

Alignment Length:	298	Identity:	118/298 - (39%)
Similarity:	182/298 - (61%)	Gaps:	22/298 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGASKV 80
            :.:||.|||....|..||.|.||.:|:|||::::..|....:|:||||||||||||||:||||:|
plant   242 NENYFGSYSSFGIHREMLSDKVRTEAYRDALLKNPTLLNGSVVMDVGCGTGILSLFAAKAGASRV 306

  Fly    81 IAVECTD-IADIAEEIIRDNQKEN------VVKVVKGLVEQVELPDGIE--KVDIIVSEWMGNAL 136
            :|||.:: :|.:|.:|.:||:..|      |::|...:||:::....|:  .||::||||||..|
plant   307 VAVEASEKMAKVATKIAKDNKVFNDNEHNGVLEVAHSMVEELDKSIQIQPHSVDVLVSEWMGYCL 371

  Fly   137 YMEAMINSVLFARDKWLTRGGRILPSTGNLWLMGAYDPHRRTNLNFWCNVEGIDMGCVRKPFSQE 201
            ..|:|::|||:|||:||..||.|||.|..:::.|.  ....|:|.||.:|.|.||..:.|....:
plant   372 LYESMLSSVLYARDRWLKPGGAILPDTATMFVAGF--GKGATSLPFWEDVYGFDMSSIGKEIHDD 434

  Fly   202 ----PLVEFVPIQQLLTDECFIHSTNLAVARNQPVEFQSNFQLK----VMRTGIINMLVLYFDVL 258
                |:|:.:..:.|:|....:.:.:||..:...|:|.:...|:    ..:|.:.:.:||:||..
plant   435 TTRLPIVDVIAERDLVTQPTLLQTFDLATMKPDEVDFTATATLEPTESEAKTRLCHGVVLWFDTG 499

  Fly   259 FPSG--KSNKSVSLTTSPHSPWTHWEQTVLHLDEPLYV 294
            |.|.  |.|.:| |:|||::|.|||.||:|...||:.|
plant   500 FTSRFCKENPTV-LSTSPYTPPTHWAQTILTFQEPISV 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	67/140 (48%)
PRMT3	NP_187835.2	zf-C2H2_2	57..>112	CDD:403839
		AdoMet_MTases	232..>330	CDD:418430	44/87 (51%)
		Methyltransf_25	284..392	CDD:404528	53/107 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820