DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and PRMT1A

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_179557.1	Gene:	PRMT1A / 816486	AraportID:	AT2G19670	Length:	366	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	124/314 - (39%)
Similarity:	193/314 - (61%)	Gaps:	5/314 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 YFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGASKVIAV 83
            ||.|||....|..||:|.||.::::|.|.::..|.:||||||||.||||||||.|:|||:.|.||
plant    48 YFDSYSHFGIHEEMLKDVVRTKSYQDVIYKNKFLIKDKIVLDVGAGTGILSLFCAKAGAAHVYAV 112

  Fly    84 ECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMINSVLFA 148
            ||:.:||.|:||::.|...:|:.|:||.:|::|||  :.|||:|:|||||..|..|.|:::||:|
plant   113 ECSQMADTAKEIVKSNGFSDVITVLKGKIEEIELP--VPKVDVIISEWMGYFLLYENMLDTVLYA 175

  Fly   149 RDKWLTRGGRILPSTGNLWLMGAYDPHRRTN-LNFWCNVEGIDMGCVRKPFSQEPLVEFVPIQQL 212
            |:|||..||.:||...:|::....|.|.:.: :.||.:|.|.||.|:::....||||:.|...|:
plant   176 RNKWLVDGGIVLPDKASLYVTAIEDAHYKDDKVEFWDDVYGFDMSCIKRRAITEPLVDTVDGNQI 240

  Fly   213 LTDECFIHSTNLAVARNQPVEFQSNFQLKVMRTGIINMLVLYFDVLFPSGKSNKSVSLTTSPHSP 277
            :||...:.:.:::........|.:.|:|...|...|:.||.||||.|.  ..:|.:..:|.|.|.
plant   241 VTDSKLLKTMDISKMAAGDASFTAPFKLVAQRNDHIHALVAYFDVSFT--MCHKKMGFSTGPKSR 303

  Fly   278 WTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRGMNFDLHISFRGERTRV 331
            .|||:||||:|::.|.:...:.:.|.:.:....::.|.::..|..|..|:...:
plant   304 ATHWKQTVLYLEDVLTICEGETITGSMTIAQNKKNPRDVDIKLSYSLNGQHCNI 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	69/131 (53%)
PRMT1A	NP_179557.1	AdoMet_MTases	87..187	CDD:100107	57/101 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54098
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11006
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890