DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and prmt2

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_012826019.1	Gene:	prmt2 / 780163	XenbaseID:	XB-GENE-980934	Length:	634	Species:	Xenopus tropicalis

Alignment Length:	324	Identity:	108/324 - (33%)
Similarity:	169/324 - (52%)	Gaps:	13/324 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KDSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAE-AGAS 78
            :|.:|:.||..|:.|:.||.|..|..|:::.|:::......|.:||:||||||:|.|.|: |...
Frog   302 QDEEYYGSYKTLKLHLEMLSDVPRTTAYKEVILRNSSSLCGKHILDLGCGTGIISFFCAKLAQPE 366

  Fly    79 KVIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMIN 143
            .|.|||.::||:....:::.|...|:|.|::...|:::||   .||||:||||||..|..|.|:.
Frog   367 AVYAVEASEIAEQTRRLVKQNGISNLVHVIRQRAEELQLP---TKVDILVSEWMGTCLLFEFMLE 428

  Fly   144 SVLFARDKWLTRGGRILPSTGNLWLMGAYDPHRRTN-LNFWCNVEGIDMGCVR----KPFSQEPL 203
            |||.|||:||...|.:.|||..:.|:.........| :.||.|...:|...::    |.|...|.
Frog   429 SVLQARDRWLKEDGVMWPSTACIHLVPCSASKEYANKVLFWDNPYQLDFSLLKPLAAKEFFARPK 493

  Fly   204 VEFV--PIQQLLTDECFIHSTNLAVARNQPVE-FQSNFQLKVMRTGIINMLVLYFDVLFPSGKSN 265
            .::|  | :..|::.|.:...||...:...:| ..|:|...|...|:::....:|.|.|.:.:..
Frog   494 PDYVLQP-EDCLSEPCILLHLNLKTLQLAELERMNSDFTFFVHTDGLLHGFTAWFSVQFQNLEEQ 557

  Fly   266 KSVSLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRGMNFDLHISFRGERT 329
            ..:.|.|.|.||.|||:.|:..|||||.|:..|::.|.:.........|.|:..|.....|:.|
Frog   558 GQLELNTGPFSPLTHWKHTLFMLDEPLQVQKGDKISGSVVFQRNSVWRRHMSVTLSWVINGKLT 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	55/132 (42%)
prmt2	XP_012826019.1	2A1904	<22..>232	CDD:273344
		SH3	235..287	CDD:388381
		Methyltransf_25	345..442	CDD:379312	46/99 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920