DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and Carm1

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_067506.2	Gene:	Carm1 / 59035	MGIID:	1913208	Length:	608	Species:	Mus musculus

Alignment Length:	332	Identity:	110/332 - (33%)
Similarity:	180/332 - (54%)	Gaps:	22/332 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EGKDSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGA 77
            |.....|||.|..|....||::|.||...::.||:|:...|:||||||||||:||||.|||:|||
Mouse   144 ESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGA 208

  Fly    78 SKVIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMI 142
            .|:.|||.:.:|..||.:::.|...:.:.|:.|.||:|.||   |:||||:||.||..|:.|.|:
Mouse   209 RKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP---EQVDIIISEPMGYMLFNERML 270

  Fly   143 NSVLFARDKWLTRGGRILPSTGNLWLMGAYDP----HRRTNLNFWC--NVEGIDMGCVR----KP 197
            .|.|.|: |:|...|.:.|:.|::.|....|.    .:.|..|||.  :..|:|:..:|    ..
Mouse   271 ESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDE 334

  Fly   198 FSQEPLVEFVPIQQLLTDECFIHSTNLAVARNQPV-EFQSNFQLKVMRTGIINMLVLYFDVLFPS 261
            :.::|:|:...| ::|..:...::.|...|:...: ..:..|:..::.:|:::.|..:|||.|..
Mouse   335 YFRQPVVDTFDI-RILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIG 398

  Fly   262 GKSNKSVSLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRGMNFDLHISFRG 326
              |..:|.|:|:|..|.|||.|.......||:.:..|.:.|...:..    .:..::|:.|..:.
Mouse   399 --SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIA----NKRQSYDISIVAQV 457

  Fly   327 ERTRVES 333
            ::|..:|
Mouse   458 DQTGSKS 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	62/131 (47%)
Carm1	NP_067506.2	CARM1	35..139	CDD:402914
		AdoMet_MTases	189..284	CDD:100107	49/98 (50%)
		Transactivation domain	500..608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820