DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and prmt9

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001124239.1	Gene:	prmt9 / 553290	ZFINID:	ZDB-GENE-080728-4	Length:	859	Species:	Danio rerio

Alignment Length:	324	Identity:	77/324 - (23%)
Similarity:	146/324 - (45%)	Gaps:	69/324 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLEGKDSDYFQSYSRLET-HMNMLRDSVRMQAFRDAIVQ--DGGLFQDKIVLDVGCGTGILSLFA 72
            |.|.|::.|..:...:|. |..||.|..|...::.||.:  :||.   ..|||:|.|||||.:.|
Zfish   137 FPEAKENFYRVANWLVERWHFLMLNDHGRNHKYQLAIKKAVEGGC---SSVLDIGTGTGILGMCA 198

  Fly    73 AEAGASKVIAVECT-DIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGI-EKVDIIVSEWMGNA 135
            ..|||::|.|.|.: .:.::|.|::..|...:.:|::......:|:|..| .:|.::|:|.:...
Zfish   199 KMAGAAEVYACELSKTMYELACEVLSANGMADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAG 263

  Fly   136 LYMEAMINSVLFARDKWL-------------TRGGRILPSTGNLWLMGAYDP----HRRTNLNFW 183
            |:.|.:|.:::.|....|             ::.||::|:...::.:....|    |.|..::
Zfish   264 LFGEGIIETLIHAWKHLLLPPPNPGELLSSPSQTGRVIPAGATVFGVAVQCPEIRRHHRLCVS-- 326

  Fly   184 CNVEGIDMGCVRKPFSQEPLVEFVPIQQLL-TDECFIHSTNLAVAR--------NQP-----VEF 234
             :|.|:|:..|.:.:|        |:..|. |::.....|...::|        .||     ::|
Zfish   327 -SVGGLDLSAVGQIYS--------PVSCLADTEDSTEPYTTERLSRLRGGYIQLTQPFTALDIDF 382

  Fly   235 QSNFQLK-------------VMRTGIINMLVLYFDVLFPSGKSNKSVSLTTSPHSPWTHWEQTV 285
            .:..:|:             |.:.||::.|.::|.:     ..::...|:|.|... |.|||.:
Zfish   383 NNVQELEGLCSREVVQLCLCVTQDGILDALAVWFQL-----HLDQDNHLSTGPQEE-TCWEQAI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	42/148 (28%)
prmt9	NP_001124239.1	TPR_11	72..135	CDD:290150
		TPR repeat	72..98	CDD:276809
		MAS20	<96..133	CDD:295844
		TPR repeat	103..133	CDD:276809
		AdoMet_MTases	151..>267	CDD:302624	37/118 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810