DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and Prmt2

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001020315.1	Gene:	Prmt2 / 499420	RGDID:	1565519	Length:	445	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	103/307 - (33%)
Similarity:	159/307 - (51%)	Gaps:	18/307 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KDSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGASK 79
            :|.:||.||..|:.|:.||.|..|...:...|:|:....:||::|||||||||:|||.|.....|
  Rat   110 QDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPK 174

  Fly    80 -VIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMIN 143
             |.|||.:|:|....:::..|...:.:.|.:..||.|.||   ||||::||||||..|..|.||.
  Rat   175 AVYAVEASDMAQHTGQLVLQNGFADTITVFQQKVEDVVLP---EKVDVLVSEWMGTCLLFEFMIE 236

  Fly   144 SVLFARDKWLTRGGRILPSTGNLWLM---GAYDPHRRTNLNFWCNVEGIDMG-----CVRKPFSQ 200
            |:|:|||.||...|.|.|:|..|.|:   ...|.|  :.:.||.|....::.     .:::.||:
  Rat   237 SILYARDAWLKEDGIIWPTTAALHLVPCSAEKDYH--SKVLFWDNAYEFNLSALKSLAIKEFFSR 299

  Fly   201 EPLVEFVPIQQLLTDECFIHSTNLAVARNQPVE-FQSNFQLKVMRTGIINMLVLYFDVLFPSGKS 264
            ......:..:..|::.|.|...::...:...:| .:...:..:.:.|.::....:|.|.|.|.:.
  Rat   300 PKSNHILKPEDCLSEPCTILQLDMRTVQVSDLETMRGELRFDIQKAGTLHGFTAWFSVHFQSLEE 364

  Fly   265 NKSVS-LTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRG--VLAMTP 308
            .:... |:|.|..|.|||:||:..:|:|:.|...|.|.|  ||...|
  Rat   365 GQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNP 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	59/132 (45%)
Prmt2	NP_001020315.1	SH3_PRMT2	46..98	CDD:212740
Prmt2	NP_001020315.1	AdoMet_MTases	153..253	CDD:100107	49/102 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820