DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and Art4

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	118/343 - (34%)
Similarity:	185/343 - (53%)	Gaps:	44/343 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EGKDSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGA 77
            |...|.|||.|..|....||::|.||...::.||:.:...||||||||||.|:||||.||.:|||
  Fly   138 ESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGA 202

  Fly    78 SKVIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMI 142
            :||.|:|.:::|..|::::..|..::.:.|:.|.:|::|||   ||||:|:||.||..||.|.|:
  Fly   203 AKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELP---EKVDVIISEPMGYMLYNERML 264

  Fly   143 NSVLFARDKWLTRGGRILPSTGNLWLMGAYD----PHRRTNLNFWCN--VEGIDMGCVR----KP 197
            .:.|.|| |||...|::.|:.|:|.:....|    ..:....|||..  ..|:|:..:.    |.
  Fly   265 ETYLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKE 328

  Fly   198 FSQEPLVEFVPIQ-----------QLLTD-ECFIHSTNLAVARNQPVEFQSNFQLKVMRTGIINM 250
            :.::|:|:...|:           ..|.| |..:|..::      |:||.      :::|||.:.
  Fly   329 YFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISI------PLEFH------ILQTGICHG 381

  Fly   251 LVLYFDVLFPSGKSNKSVSLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRG 315
            |..:|||.| || |:::|.|:|||.:|.|||.|....|..|::::....:.|.:.:....:....
  Fly   382 LAFWFDVEF-SG-SSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYD 444

  Fly   316 MNFDLHISFRGERTRVES 333
            :..||||    |.|.:.|
  Fly   445 VTIDLHI----EGTLISS 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	60/131 (46%)
Art4	NP_001262445.1	PH-like	24..134	CDD:302622
		PRMT5	53..430	CDD:282971	110/309 (36%)
		AdoMet_MTases	183..281	CDD:100107	48/101 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850