DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Art6 and Alkbh8

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001178838.1	Gene:	Alkbh8 / 366783	RGDID:	1304687	Length:	664	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	54/286 - (18%)
Similarity:	100/286 - (34%)	Gaps:	66/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LEGKDSDYFQSYSRLETHMNMLRDS--VRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAE 74
            ||.:.......|..:.:|.:..|.|  .|:..|..|      |....||.|:|||.|      ..
  Rat   368 LELEQKHVHHVYDEIASHFSSTRHSPWPRIVEFLKA------LPSGSIVADIGCGNG------KY 420

  Fly    75 AGASKVIAVECTDIADIAEEIIRDNQKENVV-------------------KVVKGLVEQVELPDG 120
            .|.:|.:.:...|.:....:|.|:.|.:.:|                   .|:..........:.
  Rat   421 LGINKELYMIGCDRSRNLVDICRERQFQALVCDALAVPVRSGSCDACISIAVIHHFATAERRVEA 485

  Fly   121 IEKVDIIVSEWMGNALYMEAMINSVLFARDKWLTRGGRILPSTGNLWLMGAYDPHRRTNLNFWCN 185
            ::::..::.......:|:.||.......:.|:| :|.||  |.|:           :..||...:
  Rat   486 LQEIARLLRSGGQALIYVWAMEQEYRDQKSKYL-KGNRI--SQGD-----------KGELNSATS 536

  Fly   186 VEGIDMGCVRKPFSQEPLVEFVPIQQLLTDECFIHSTNLAVARNQPVEFQSNFQLKVMRTGIINM 250
            :|.:.:..:.:..|::|.:..........:||          :::.| ..|...:...||...:.
  Rat   537 MEQLLVNQMPEGVSEDPGLSVHSSNNTKDEEC----------KSRKV-LNSELPIHTNRTCFHSQ 590

  Fly   251 LVLYFDVLFP---SGKSNKSVSLTTS 273
                 |||.|   .||..|..::..|
  Rat   591 -----DVLVPWHLKGKPGKDKAVEQS 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	30/152 (20%)
Alkbh8	NP_001178838.1	DUF1891	1..37	CDD:117570
		RRM_ALKBH8	42..122	CDD:240877
		2OG-FeII_Oxy	152..334	CDD:304390
		Methyltransf_11	412..501	CDD:285453	13/94 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900