DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and Prmt9

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001178528.1	Gene:	Prmt9 / 291947	RGDID:	1306157	Length:	841	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	92/373 - (24%)
Similarity:	175/373 - (46%)	Gaps:	60/373 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLEGKDSDYFQSYSRLET-HMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAE 74
            |.:.|::.|..:...:|. |..||.|:.|.:.: :|.:|.......|.|||:|.||||||:||.:
  Rat   134 FNDAKENFYRVANWLVERWHFIMLNDTKRNEIY-NAAIQKAVRLGSKTVLDIGAGTGILSMFAKK 197

  Fly    75 AGASKVIAVECT-DIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGI-EKVDIIVSEWMGNALY 137
            |||..|.|.|.: .:.::|.:::..|:.|:.::::......:|:|..| |:|.::|:|.:...::
  Rat   198 AGAHSVYACELSKTMYELACDVVAANKMEDGIRLLHMKSLDLEIPKHIPERVSLVVTETVDAGVF 262

  Fly   138 MEAMINSVLFARDKWL----TRG--------GRILPSTGNLWLM-------------GAYD---P 174
            .|.::.|::.|.:..|    |:|        |:::|::..:..|             .|.|   .
  Rat   263 GEGIVESLIHAWEHLLLQPQTKGESGSWGKYGKVIPASAVISGMAVECAEIRRHHRVSAKDIAGI 327

  Fly   175 HRRTNLNFWCNV-EGIDMGCVRKPFSQEPLVEFVPIQQLLTDECF----IHSTNLAVARNQPVEF 234
            |..||:.|.... ..:|.....:|::.|.:.......:.|| |||    :...||...::.....
  Rat   328 HLPTNVRFQSPAYASVDPEETVEPYTTEKMSGIPGGYRPLT-ECFQIMKVDFNNLQELKSLATRK 391

  Fly   235 QSNFQLKVMRTGIINMLVLYFDVLFPSGKSNKSVSLTTSPHSPWTHWEQTVLHLD--EPLYVRIR 297
            ..:..:..::.|.::.::::| ||    :.:...||:||| |..|.|||.|..:.  |..:::..
  Rat   392 PHSLSVPAVKEGTLDAIMVWF-VL----QLDDEHSLSTSP-SEETCWEQAVYPVQALEDYWIQPG 450

  Fly   298 DRVRGVLAMTPTGQDG----RGMNFDLHISFRGERTRVESFKSFSSPR 341
            |:|    .|..:..|.    :|::. ||:..     .:|..|||:..:
  Rat   451 DQV----TMEASCHDCYLRIQGISI-LHLEH-----EMEVIKSFTKSK 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	43/145 (30%)
Prmt9	NP_001178528.1	TPR_11	68..132	CDD:290150
		TPR repeat	68..95	CDD:276809
		TPR repeat	100..130	CDD:276809
		AdoMet_MTases	148..>338	CDD:302624	52/190 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810