DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and AgaP_AGAP008846

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_319588.4	Gene:	AgaP_AGAP008846 / 1279809	VectorBaseID:	AGAP008846	Length:	356	Species:	Anopheles gambiae

Alignment Length:	315	Identity:	114/315 - (36%)
Similarity:	178/315 - (56%)	Gaps:	15/315 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEAGASKVI 81
            :.||.||..|:.|..||.|..|.:|::.||:.:..||:.|.|||||.||||||:|.|:||||||.
Mosquito    12 ASYFDSYEDLKVHELMLTDQPRQEAYQKAILGNRALFEGKTVLDVGAGTGILSIFCAQAGASKVY 76

  Fly    82 AVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNALYMEAMINSVL 146
            |||.:::|.:|..::.:||.:.|::|.:..||..:||:| |:||||||||||..|..|.|::|||
Mosquito    77 AVEASNLARLARAVVEENQLQAVIEVSECKVEDFQLPEG-ERVDIIVSEWMGFFLLHEGMLDSVL 140

  Fly   147 FARDKWLTRGGRILPSTGNLWLMGAYDPHRRTNLNFWCNVEGIDMGC----VRKPFSQEPLVEFV 207
            :||||:|...|.:.|.|..|::.....|.|   .:.|.::.|:.|.|    :|:..|..|.|..|
Mosquito   141 YARDKFLKPNGLMFPDTATLYVAPCSVPSR---FDRWESLSGVSMRCFGRALREQNSGNPEVLTV 202

  Fly   208 PIQQLLTDECFIHSTNLAVARNQPVEFQSNFQLK----VMRTGIINMLVLYFDVLFPSGKSNKSV 268
            ..:.||.|...|...:|.....:.:   ::.::|    ..|:|.:....::|:..||...:.:.:
Mosquito   203 APEHLLYDGHIIAWFDLMEVTTEEL---NSIEVKDVIVASRSGKLQGFCIWFECTFPGDGAEEQL 264

  Fly   269 SLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGRGMNFDLHIS 323
            .|:|||.:..|||:|||:.|.|.....:.:|.....::|.|........:||.::
Mosquito   265 QLSTSPSASETHWKQTVIPLPEDACEELEERDPVAFSLTMTRNKETNRRYDLQLT 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	67/131 (51%)
AgaP_AGAP008846	XP_319588.4	Methyltransf_18	49..154	CDD:289607	57/105 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54098
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830