DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art6 and Prmt9

DIOPT Version :9

Sequence 1:	NP_650322.1	Gene:	Art6 / 41699	FlyBaseID:	FBgn0038189	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001074709.1	Gene:	Prmt9 / 102182	MGIID:	2142651	Length:	846	Species:	Mus musculus

Alignment Length:	328	Identity:	84/328 - (25%)
Similarity:	157/328 - (47%)	Gaps:	46/328 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLEGKDSDYFQSYSRLET-HMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAE 74
            |.:.|::.|..:...:|. |..||.|:.|...: :|.:|.......:.|||:|.||||||:||.:
Mouse   134 FNDAKENFYRVANWLVERWHFIMLNDTRRNMVY-NAAIQKAVCLGSRTVLDIGTGTGILSMFAKK 197

  Fly    75 AGASKVIAVECT-DIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGI-EKVDIIVSEWMGNALY 137
            |||..|.|.|.: .:.::|.:::..|:.||.:|::......:|:|..| |:|.::|:|.:...::
Mouse   198 AGAQSVYACELSKTMYELACDVVAANKMENGIKLLHMKSLDIEIPKHIPERVSLVVTETVDAGVF 262

  Fly   138 MEAMINSVLFARDKWLT------------RGGRILPSTGNLWLM-------------GAYD---P 174
            .|.::.|::.|.:..|.            :.|:::|:...::.|             ||.|   .
Mouse   263 GEGIVESLIHAWEHLLLQPKTKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGI 327

  Fly   175 HRRTNLNFWCNV-EGIDMGCVRKPFSQEPLVEFVPIQQLLTDECF----IHSTNLAVARNQPVEF 234
            |..||:.|.... ..:|.....:|::.|.: ..:|...|...|||    :...||...::...:.
Mouse   328 HLPTNVKFQSPAYTSVDTEETVEPYTTEKM-SGIPGGYLPLTECFQIMKVDFNNLQELKSLATKK 391

  Fly   235 QSNFQLKVMRTGIINMLVLYFDVLFPSGKSNKSVSLTTSPHSPWTHWEQTVLHLD--EPLYVRIR 297
            ..:..:..::.|:::.::::| ||    :.:...||:||| |..|.|||.|..:.  |...::..
Mouse   392 PHSLNVPAIKEGVLDAIMVWF-VL----QLDDEYSLSTSP-SEETCWEQAVYPVQALEDYCIQPG 450

  Fly   298 DRV 300
            |||
Mouse   451 DRV 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art6	NP_650322.1	AdoMet_MTases	29..>161	CDD:302624	42/145 (29%)
Prmt9	NP_001074709.1	TPR 1	25..58
		TPR 2	67..100
		TPR_11	68..132	CDD:290150
		TPR repeat	68..95	CDD:276809
		TPR repeat	100..130	CDD:276809
		TPR 3	101..134		84/328 (26%)
		AdoMet_MTases	148..>303	CDD:302624	44/155 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810